Teratocarcinoma F9 cells induced to differentiate with sodium butyrate produce both tissue‐type and urokinase‐type plasminogen activators

Masashi Takeda, Mitsuko Kosaka, Yukio Nishina, Ken Sawada, Keishi Matsumoto, Yoshitake Nishimune

研究成果 › 査読

7 被引用数 (Scopus)

抄録

Sodium butyrate (NaB) can induce teratocarcinoma cell differentiation as retinoic acid (RA). However, the function of these two agents seems to be a little different [Kosaka et al., Exp Cell Res, 192 : 46–51, 1991]. F9 cells treated with NaB synthesize both tissue‐type (tPA) and urokinase‐type (uPA) plasminogen activator, though RA induces only tPA production. Urokinase‐type PA is demonstrated to exist in association with membrane and to localize its activity to the close environment of the cell surface. This may cause the specific cell morphology and characteristics of differentiated F9 cells induced with NaB.

本文言語English
ページ（範囲）284-289
ページ数6
ジャーナルJournal of Cellular Biochemistry
巻49
号3
DOI
出版ステータスPublished - 7月 1992
外部発表はい

ASJC Scopus subject areas

  • 生化学
  • 分子生物学
  • 細胞生物学

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