@article{abe4955607ac4258b8aa284553104698,
title = "Symbiodinolactone A, a new 12-membered macrolide from symbiotic marine dinoflagellate Symbiodinium sp.",
abstract = "A new 12-membered macrolide, symbiodinolactone A, was isolated from the culture broth of symbiotic marine dinoflagellate Symbiodinium sp. The gross structure of symbiodinolactone A was elucidated by spectroscopic analyses, and the relative configuration was elucidated by the J-based configuration analysis and density-functional theory calculations. Symbiodinolactone A is the new 12-membered macrolide possessing an E double bond between C-4 and C-5, a branched methyl group at C-7, and a 1,2,3-trihydroxybutyl group at C-11. Symbiodinolactone A is the first usual size macrolide and the first non-nitrogen-containing macrolide from dinoflagellate Symbiodinium sp. Symbiodinolactone A might be generated by the unexplained dinoflagellate polyketide biosynthetic machinery.",
keywords = "Dinoflagellate, Macrolide, Symbiodinium sp., Symbiodinolactone A, Symbiotic",
author = "Kurimoto, {Shin ichiro} and Yurika Iinuma and Jun'ichi Kobayashi and Takaaki Kubota",
note = "Funding Information: We thank Mr. K. Chiba, The Instrument Analysis Equipment Research Center, Showa Pharmaceutical University, for measurements of MS. This work was partly supported by the Naito Foundation, the Shorai Foundation for Science and Technology, a Grant-in-Aid for Young Scientists of Showa Pharmaceutical University, MEXT-Supported Program for the Strategic Research Foundation at Private Universities (2013–2017), and JSPS KAKENHI Grant Number JP17K08345. Funding Information: We thank Mr. K. Chiba, The Instrument Analysis Equipment Research Center, Showa Pharmaceutical University, for measurements of MS. This work was partly supported by the Naito Foundation, the Shorai Foundation for Science and Technology, a Grant-in-Aid for Young Scientists of Showa Pharmaceutical University, MEXT-Supported Program for the Strategic Research Foundation at Private Universities (2013?2017), and JSPS KAKENHI Grant Number JP17K08345. Funding Information: We thank Mr. K. Chiba, The Instrument Analysis Equipment Research Center, Showa Pharmaceutical University, for measurements of MS. This work was partly supported by the Naito Foundation , the Shorai Foundation for Science and Technology , a Grant-in-Aid for Young Scientists of Showa Pharmaceutical University, MEXT -Supported Program for the Strategic Research Foundation at Private Universities ( 2013–2017 ), and JSPS KAKENHI Grant Number JP17K08345 . Publisher Copyright: {\textcopyright} 2018 Elsevier Ltd",
year = "2018",
month = dec,
day = "19",
doi = "10.1016/j.tetlet.2018.11.018",
language = "English",
volume = "59",
pages = "4496--4499",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "51",
}
