@article{e94de17b1f264731a8ee4f3850422600,
title = "Structure-activity relationship of indoloquinoline analogs anti-MRSA",
abstract = "Indolo[3,2-b]quinoline analogs (3a-3s), 4-(acridin-9-ylamino) phenol hydrochloride (4), benzofuro[3,2-b]quinoline (3t), indeno[1,2-b]quinolines (3u and 3v) have been synthesized. Those compounds were found to exhibit anti-bacterial activity towards Methicillin-resistant Staphylococcus aureus (anti-MRSA activity). Structure-activity relationship studies were conducted that indoloquinoline ring, benzofuroquinoline ring and 4-aminophenol group are essential structure for anti-MRSA activity.",
keywords = "Anti-MRSA, Benzofuroquinoline, Indenoquinoline, Indoloquinoline, Structure-activity",
author = "Min Zhao and Tomonori Kamada and Aya Takeuchi and Hiromi Nishioka and Teruo Kuroda and Yasuo Takeuchi",
note = "Funding Information: This work was supported by Graduate School of Medicine , Dentistry and Pharmaceutical Sciences , Okayama University and the SC-NMR laboratory of Okayama University for using of the facilities. The authors are grateful to Ms. Megumi Kosaka and Mr. Motonari Kobayashi at Division of Instrumental Analysis for the measurements of elemental analyses, and the MS measurements. Publisher Copyright: {\textcopyright} 2015 Elsevier Ltd. All rights reserved. Copyright: Copyright 2017 Elsevier B.V., All rights reserved.",
year = "2015",
month = dec,
day = "1",
doi = "10.1016/j.bmcl.2015.10.058",
language = "English",
volume = "25",
pages = "5551--5554",
journal = "Bioorganic and Medicinal Chemistry Letters",
issn = "0960-894X",
publisher = "Elsevier Limited",
number = "23",
}