@article{4a466709121943a299c6583f3977c6ed,
title = "Regioselective 1,3-dipolar cycloaddition of nitriles with nitrile imines generated from tetrazoles",
abstract = "A synthesis of 3,5-disubstituted-1,2,4-triazoles from nitriles and 5-aryltetrazoles is reported. When 5-aryltetrazoles are triflylated in the presence of nitriles, the resulting 5-aryl-2-triflyltetrazoles thermally generate N-triflyl-nitrile imines through a sequence of ring-chain tautomerization and denitrogenation. The N-triflyl-nitrile imines immediately undergo 1,3-dipolar cycloaddition with nitriles in a regioselective manner, forming the corresponding 1,2,4-triazoles.",
keywords = "Cycloaddition, Nitrile imines, Tetrazoles",
author = "Tomoya Miura and Kohei Hagiwara and Takayuki Nakamuro and Yuuya Nagata and Naoki Oku and Masahiro Murakami",
note = "Funding Information: This work was supported in part by MEXT [Grants-in-Aid for Scientific Research (B) (20H02739) (TM)], JST-ERATO (No. JPMJER1903) (YN), and JSPS-WPI (YN). TN acknowledges JSPS fellowship for young scientists. Publisher Copyright: {\textcopyright} 2021 The Chemical Society of Japan",
year = "2021",
month = jan,
doi = "10.1246/CL.200634",
language = "English",
volume = "50",
pages = "131--135",
journal = "Chemistry Letters",
issn = "0366-7022",
publisher = "Chemical Society of Japan",
number = "1",
}