The purpose of this article is to review regional variation in oral mucosal drug permeability. The structure and composition of the mucosa at different sites in the oral cavity, factors affecting mucosal permeability, selection of appropriate experimental systems for studying mucosal permeability, and formulation factors including penetration enhancement relevant to the design of systems for oral mucosal delivery are reviewed.
|ジャーナル||Critical Reviews in Therapeutic Drug Carrier Systems|
|出版ステータス||Published - 11月 25 2000|
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