抄録
We evaluated quantitatively the liver injury of rats induced by ischemia-reperfusion, using 99mTc-DTPA-Galactosyl-Human-Serum-Albumin (99mTc-GSA). The vessels of the left lobe were clamped for 5, 10, or 45 minutes followed by 15 minutes reperfusion. Then, 99mTc-GSA was intravenously administered (170 micrograms/kg body weight) to rats. Two compartment analysis was made on measurement curves in the heart and liver to obtain clearance parameters. Significant difference was observed between the ischemic group (clamped for 10 and for 45 minutes) and the control. These results suggest that 99mTc-GSA is useful in the estimation of liver injury produced by ischemia-reperfusion.
| 本文言語 | English |
|---|---|
| ページ（範囲） | 503-504 |
| ページ数 | 2 |
| ジャーナル | Nippon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica |
| 巻 | 52 |
| 号 | 4 |
| 出版ステータス | Published - 4月 25 1992 |
ASJC Scopus subject areas
- 放射線学、核医学およびイメージング
- 腫瘍学