Pathogenesis of Severe Liver Injury in Patients with Anorexia Nervosa: A Report of Two Cases and a Literature Review

Masahiro Sakata; Akinobu Takaki; Atsushi Oyama; Takuya Adachi; Nozomu Wada; Yasuto Takeuchi; Tetsuya Yasunaka; Hideki Onishi; Hidenori Shiraha; Hiroyuki Okada

doi:10.2739/kurumemedj.MS6723011

Pathogenesis of Severe Liver Injury in Patients with Anorexia Nervosa: A Report of Two Cases and a Literature Review

Masahiro Sakata, Akinobu Takaki, Atsushi Oyama, Takuya Adachi, Nozomu Wada, Yasuto Takeuchi, Tetsuya Yasunaka, Hideki Onishi, Hidenori Shiraha, Hiroyuki Okada

研究成果 › 査読

抄録

Anorexia nervosa (AN) can cause severe protein energy malnutrition and the consequent development of various organ disorders. AN is known to cause hepatic complications. We report two cases of starvation and refeeding-induced liver injury in patients with AN, and review the literature on the hepatic complications of AN. Acute liver injury can be induced by both starvation and refeeding, although the underlying pathomechanisms and management of liver injury differ between these two conditions. Clinicians should carefully identify the clinical features to ensure an accurate diagnosis and appropriate management of these conditions.

本文言語	English
ページ（範囲）	121-129
ページ数	9
ジャーナル	Kurume Medical Journal
巻	67
号	2-3
DOI	https://doi.org/10.2739/kurumemedj.MS6723011
出版ステータス	Published - 2020

ASJC Scopus subject areas

医学（全般）

UN SDG

この成果は、次の持続可能な開発目標に貢献しています

文献へのアクセス

10.2739/kurumemedj.MS6723011

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abstract = "Anorexia nervosa (AN) can cause severe protein energy malnutrition and the consequent development of various organ disorders. AN is known to cause hepatic complications. We report two cases of starvation and refeeding-induced liver injury in patients with AN, and review the literature on the hepatic complications of AN. Acute liver injury can be induced by both starvation and refeeding, although the underlying pathomechanisms and management of liver injury differ between these two conditions. Clinicians should carefully identify the clinical features to ensure an accurate diagnosis and appropriate management of these conditions.",

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AU - Sakata, Masahiro

AU - Takaki, Akinobu

AU - Oyama, Atsushi

AU - Adachi, Takuya

AU - Wada, Nozomu

AU - Takeuchi, Yasuto

AU - Yasunaka, Tetsuya

AU - Onishi, Hideki

AU - Shiraha, Hidenori

AU - Okada, Hiroyuki

PY - 2020

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AB - Anorexia nervosa (AN) can cause severe protein energy malnutrition and the consequent development of various organ disorders. AN is known to cause hepatic complications. We report two cases of starvation and refeeding-induced liver injury in patients with AN, and review the literature on the hepatic complications of AN. Acute liver injury can be induced by both starvation and refeeding, although the underlying pathomechanisms and management of liver injury differ between these two conditions. Clinicians should carefully identify the clinical features to ensure an accurate diagnosis and appropriate management of these conditions.

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KW - hepatic complication

KW - refeeding syndrome

KW - starvation induced liver injury

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Pathogenesis of Severe Liver Injury in Patients with Anorexia Nervosa: A Report of Two Cases and a Literature Review

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ASJC Scopus subject areas

UN SDG

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