Multifunctional cytotoxic agents from Anacardium occidentale

Isao Kubo, Teruhiko Nitoda, Felismino E. Tocoli, Ivan R. Green

研究成果査読

28 被引用数 (Scopus)

抄録

The effects of anacardic acids and cardols isolated from the cashew nut and apple Anacardium occidentale (Anacardiaceae) on murine B16-F10 melanoma cells were tested. Although anacardic acids and cardols were found to inhibit tyrosinase, a key enzyme in melanin synthesis, melanogenesis in melanocytes was not suppressed in cultured cells but rather enhanced. Both anacardic acids and cardols exhibited moderate cytotoxicity.

本文言語English
ページ(範囲)38-45
ページ数8
ジャーナルPhytotherapy Research
25
1
DOI
出版ステータスPublished - 1月 1 2011
外部発表はい

ASJC Scopus subject areas

  • 薬理学

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