TY - JOUR
T1 - Multifocal dysembryoplastic neuroepithelial tumor showing various imaging findings
T2 - A case report
AU - Sasaki, Tatsuya
AU - Kameda, Masahiro
AU - Tomita, Yosuke
AU - Hosomoto, Kakeru
AU - Hayashi, Yumiko
AU - Endoh, Fumika
AU - Oka, Makio
AU - Tomita, Yusuke
AU - Yasuhara, Takao
AU - Agari, Takashi
AU - Kobayashi, Katsuhiro
AU - Date, Isao
N1 - Publisher Copyright:
© 2018, Japanese Congress of Neurological Surgeons. All rights reserved.
PY - 2018
Y1 - 2018
N2 - Dysembryoplastic neuroepithelial tumor (DNT) is a type of brain tumor that causes refractory epilepsy. We present the case of a 13-year-old boy with temporal lobe epilepsy. Magnetic resonance imaging (MRI) revealed multiple lesions in the right temporal lobe, basal ganglia, deep white matter, and lateral ventricle. Serial MRI showed morphological changes of contrast-enhanced lesions, but fluorodeoxyglucose-positron emission tomography (FDG-PET) revealed hypometabolic lesions. Subtraction ictal single-photon emission computed tomography coregistered to MRI (SISCOM) and ictal electroencephalography (EEG) suggested the seizure onset zone might be located in the right temporal lobe. We performed right temporal lobectomy, and pathological diagnosis confirmed DNT. At one year post-surgery, the patient has achieved seizure-free status, and the remaining lesions have not increased. Multifocal DNT is extremely rare, and treatment strategy was difficult to determine in this case. Surgery should be performed when appropriate after clarifying the treatment purpose.
AB - Dysembryoplastic neuroepithelial tumor (DNT) is a type of brain tumor that causes refractory epilepsy. We present the case of a 13-year-old boy with temporal lobe epilepsy. Magnetic resonance imaging (MRI) revealed multiple lesions in the right temporal lobe, basal ganglia, deep white matter, and lateral ventricle. Serial MRI showed morphological changes of contrast-enhanced lesions, but fluorodeoxyglucose-positron emission tomography (FDG-PET) revealed hypometabolic lesions. Subtraction ictal single-photon emission computed tomography coregistered to MRI (SISCOM) and ictal electroencephalography (EEG) suggested the seizure onset zone might be located in the right temporal lobe. We performed right temporal lobectomy, and pathological diagnosis confirmed DNT. At one year post-surgery, the patient has achieved seizure-free status, and the remaining lesions have not increased. Multifocal DNT is extremely rare, and treatment strategy was difficult to determine in this case. Surgery should be performed when appropriate after clarifying the treatment purpose.
KW - Dysembryoplastic neuroepithelial tumor
KW - Multifocal
KW - Temporal lobe epilepsy
UR - http://www.scopus.com/inward/record.url?scp=85046127771&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85046127771&partnerID=8YFLogxK
U2 - 10.7887/jcns.27.317
DO - 10.7887/jcns.27.317
M3 - Article
AN - SCOPUS:85046127771
SN - 0917-950X
VL - 27
SP - 317
EP - 322
JO - Japanese Journal of Neurosurgery
JF - Japanese Journal of Neurosurgery
IS - 4
ER -