Modulation and transmission of sweet taste information for energy homeostasis

Keisuke Sanematsu, Nao Horio, Yoshihiro Murata, Ryusuke Yoshida, Tadahiro Ohkuri, Noriatsu Shigemura, Yuzo Ninomiya

研究成果

9 被引用数 (Scopus)

抄録

Perception of sweet taste is important for animals to detect external energy source of calories. In mice, sweet-sensitive cells possess a leptin receptor. Increase of plasma leptin with increasing internal energy storage in the adipose tissue suppresses sweet taste responses via this receptor. Data from our recent studies indicate that leptin may also modulate sweet taste sensation in humans with a diurnal variation in sweet sensitivity. This leptin modulation of sweet taste information to the brain may influence individuals' preference and ingestive behavior, thereby playing important roles in regulation of energy homeostasis.

本文言語English
ホスト出版物のタイトルInternational Symposium on Olfaction and Taste
出版社Blackwell Publishing Inc.
ページ102-106
ページ数5
ISBN(印刷版)9781573317382
DOI
出版ステータスPublished - 7月 2009
外部発表はい

出版物シリーズ

名前Annals of the New York Academy of Sciences
1170
ISSN(印刷版)0077-8923
ISSN(電子版)1749-6632

ASJC Scopus subject areas

  • 神経科学(全般)
  • 生化学、遺伝学、分子生物学(全般)
  • 科学史および科学哲学

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