@article{8b9bdedf6d45476e8ec1264b719a43d0,
title = "In vivo microdialysis measures of extracellular serotonin in the rat hippocampus during sleep-wakefulness",
abstract = "We investigated extracellular 5-hydroxytryptamine (5-HT) levels in rat hippocampus during different stages of the sleep-waking cycle using in vivo microdialysis. The extracellular 5-HT level was highest in active waking (AW) and, when compared to AW, 5-HT level was progressively lower in quiet waking (QW; 78%), quiet sleep (QS; 50%) and REM (which we termed active sleep (AS); 40%). Functional implications of AS related-decreased 5-HT in the hippocampus are discussed.",
keywords = "Hippocampus, Microdialysis, Rat, Serotonin, Sleep",
author = "Park, {Sung Pa} and Faustino Lopez-Rodriguez and Wilson, {Charles L.} and Nigel Maidment and Yosuke Matsumoto and Jerome Engel",
note = "Funding Information: We wish to thank Joyel Almajano for technical assistance, Toan Do and Larry Ackerson for HPLC analysis, and Tony Fields for EEG recording assistance. Faustino Lopez-Rodriguez was supported by a Program in Minority Research Training in Psychiatry Fellowship, funded by NIMH, MH 19126. Funding was provided by NIH grants NS 33310 and NS 02808. ",
year = "1999",
month = jul,
day = "3",
doi = "10.1016/S0006-8993(99)01511-5",
language = "English",
volume = "833",
pages = "291--296",
journal = "Molecular Brain Research",
issn = "0006-8993",
publisher = "Elsevier",
number = "2",
}