@article{0bb65dffa16a4f0989f659a4f40c75c6,
title = "In vitro antiplasmodial activity of antimalarial medicinal plants used in Vietnamese traditional medicine",
abstract = "Among 42 extracts, prepared from 14 medicinal plants used in Vietnamese traditional medicine to treat malaria, 24 were found to have antiplasmodial activity by inhibiting the growth of the chloroquine-resistant Plasmodium falciparum strain FCR-3 with EC50 values less than 10μg/ml. Each medicinal plant possessed at least one active extract. The methanol extract of Coscinium fenestratum had the strongest antiplasmodial activity with EC50 value of 0.5μg/ml. Activity-guided fractionation led to identification of berberine as the major active constituent.",
keywords = "Antimalaria, Antiplasmodial, FCR-3, Plasmodium falciparum, Vietnamese medicinal plants",
author = "Tran, {Quan Le} and Yasuhiro Tezuka and Ueda, {Jun Ya} and Nguyen, {Nhan Trung} and Yukiko Maruyama and Khurshida Begum and Kim, {Hye Sook} and Yusuke Wataya and Tran, {Qui Kim} and Shigetoshi Kadota",
note = "Funding Information: This work was supported by a Grant-in-Aid for International Scientific Research (No. 13576027) and for Scientific Research on Priority Area (No. 14021072) from Ministry of Education, Culture, Sports, Science and Technology, Japan. ",
year = "2003",
month = jun,
doi = "10.1016/S0378-8741(03)00045-X",
language = "English",
volume = "86",
pages = "249--252",
journal = "Journal of Ethnopharmacology",
issn = "0378-8741",
publisher = "Elsevier Ireland Ltd",
number = "2-3",
}
