@article{dcfaf68c9ad646d38e578ddf097c68cc,
title = "Fulminant Respiratory Failure Caused by Anti-asparaginyl tRNA Synthetase (Anti-KS) Antibody Syndrome-related Interstitial Lung Disease",
abstract = "Anti-asparaginyl transfer RNA (tRNA) synthetase (KS) antibodies, detected in <5% patients with antiaminoacyl- tRNA synthetase antibody syndrome, are strongly associated with interstitial pneumonia but not myositis and skin symptoms. A recent report suggested that most patients with interstitial pneumonia and anti-KS antibody (KS-ILD) may present with chronic disease. We herein report a rare case of severe acute respiratory failure in a KS-ILD patient requiring extracorporeal membrane oxygenation (ECMO). ECMO is useful for facilitating not only lung rest until recovery but also the definitive diagnosis and treatment of ILD. KS-ILD can develop acutely with fulminant respiratory failure, as observed in this case.",
keywords = "anti-ARS antibody syndrome, anti-asparaginyl tRNA synthetase antibody, anti-KS antibody, extracorporeal membrane oxygenation, interstitial pneumonia",
author = "Naohiro Oda and Akihiko Taniguchi and Toshiyuki Aokage and Satoru Senoo and Kenta Nagashima and Reo Mitani and Ichiro Takata and Nobuaki Miyahara",
note = "Funding Information: We thank Ran Nakashima (Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University Kyoto, Japan) for measuring the anti-ARS antibody levels. Publisher Copyright: {\textcopyright} 2022 The Japanese Society of Internal Medicine.",
year = "2022",
doi = "10.2169/internalmedicine.9239-21",
language = "English",
volume = "61",
pages = "3409--3414",
journal = "Internal Medicine",
issn = "0918-2918",
publisher = "Japanese Society of Internal Medicine",
number = "22",
}