Enantioselective Steglich Rearrangement of Oxindole Derivatives by Easily Accessible Chiral N,N-4-(Dimethylamino)pyridine Derivatives

Hiroki Mandai; Takuma Fujiwara; Katsuaki Noda; Kazuki Fujii; Koichi Mitsudo; Toshinobu Korenaga; Seiji Suga

doi:10.1021/acs.orglett.5b02089

Enantioselective Steglich Rearrangement of Oxindole Derivatives by Easily Accessible Chiral N,N-4-(Dimethylamino)pyridine Derivatives

Hiroki Mandai, Takuma Fujiwara, Katsuaki Noda, Kazuki Fujii, Koichi Mitsudo, Toshinobu Korenaga, Seiji Suga

研究成果 › 査読

34 被引用数 (Scopus)

抄録

Chiral N,N-4-(dimethylamino)pyridine (DMAP) derivatives, which can be readily prepared by the Ugi multicomponent reaction in a one-pot manner, have been efficiently applied to the enantioselective Steglich rearrangement of oxindole derivatives to give the desired products bearing a quaternary carbon center in high yield (>98% yield) and with high enantioselectivity (up to 99:1 er).

本文言語	English
ページ（範囲）	4436-4439
ページ数	4
ジャーナル	Organic Letters
巻	17
号	18
DOI	https://doi.org/10.1021/acs.orglett.5b02089
出版ステータス	Published - 9月 18 2015

ASJC Scopus subject areas

生化学
物理化学および理論化学
有機化学

文献へのアクセス

10.1021/acs.orglett.5b02089

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引用スタイル

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abstract = "Chiral N,N-4-(dimethylamino)pyridine (DMAP) derivatives, which can be readily prepared by the Ugi multicomponent reaction in a one-pot manner, have been efficiently applied to the enantioselective Steglich rearrangement of oxindole derivatives to give the desired products bearing a quaternary carbon center in high yield (>98% yield) and with high enantioselectivity (up to 99:1 er).",

author = "Hiroki Mandai and Takuma Fujiwara and Katsuaki Noda and Kazuki Fujii and Koichi Mitsudo and Toshinobu Korenaga and Seiji Suga",

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AU - Noda, Katsuaki

AU - Fujii, Kazuki

AU - Mitsudo, Koichi

AU - Korenaga, Toshinobu

AU - Suga, Seiji

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