Crohn's Disease Associated with Growth Hormone Secretory Dysfunction

Toshio Ogura; Yasuo Itano; Takayoshi Yamauchi; Tetsuya Oishi; Tetsushi Aita; Nobuhiko Hayakawa; Takashi Ogasa; Kosuke Ota; Zensuke Ota; Jingo Kageyama; Kozo Hashimoto

doi:10.2169/internalmedicine.34.112

Crohn's Disease Associated with Growth Hormone Secretory Dysfunction

Toshio Ogura, Yasuo Itano, Takayoshi Yamauchi, Tetsuya Oishi, Tetsushi Aita, Nobuhiko Hayakawa, Takashi Ogasa, Kosuke Ota, Zensuke Ota, Jingo Kageyama, Kozo Hashimoto

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研究成果 › 査読

6 被引用数 (Scopus)

抄録

A 10-year-old boy presented in 1989 with repeated episodes of vomiting, abdominal distension and severe growth retardation. Endocrinologic examination indicated growth hormone (GH) secretory dysfunction. Administration of recombinant human GH (rhGH) led to growth, but the patient discontinued treatment. He was readmitted to our hospital in 1993, at the age of 16. His stature was very short. Laboratory findings suggested malnutrition. Radiologic examination revealed regional stenosis and a cobblestone appearance of the intestine. The histologic diagnosis was compatible with Crohn's disease. Administration of prednisolone alleviated gastrointestinal symptoms with the improvement of GH secretory function.

本文言語	English
ページ（範囲）	112-117
ページ数	6
ジャーナル	Internal Medicine
巻	34
号	2
DOI	https://doi.org/10.2169/internalmedicine.34.112
出版ステータス	Published - 1995

ASJC Scopus subject areas

内科学

UN SDG

この成果は、次の持続可能な開発目標に貢献しています

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10.2169/internalmedicine.34.112

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引用スタイル

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title = "Crohn's Disease Associated with Growth Hormone Secretory Dysfunction",

abstract = "A 10-year-old boy presented in 1989 with repeated episodes of vomiting, abdominal distension and severe growth retardation. Endocrinologic examination indicated growth hormone (GH) secretory dysfunction. Administration of recombinant human GH (rhGH) led to growth, but the patient discontinued treatment. He was readmitted to our hospital in 1993, at the age of 16. His stature was very short. Laboratory findings suggested malnutrition. Radiologic examination revealed regional stenosis and a cobblestone appearance of the intestine. The histologic diagnosis was compatible with Crohn's disease. Administration of prednisolone alleviated gastrointestinal symptoms with the improvement of GH secretory function.",

keywords = "glucocorticoid therapy, neurosecretory dysfunction, pituitary dwarfism, short stature",

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T1 - Crohn's Disease Associated with Growth Hormone Secretory Dysfunction

AU - Ogura, Toshio

AU - Itano, Yasuo

AU - Yamauchi, Takayoshi

AU - Oishi, Tetsuya

AU - Aita, Tetsushi

AU - Hayakawa, Nobuhiko

AU - Ogasa, Takashi

AU - Ota, Kosuke

AU - Ota, Zensuke

AU - Kageyama, Jingo

AU - Hashimoto, Kozo

PY - 1995

Y1 - 1995

N2 - A 10-year-old boy presented in 1989 with repeated episodes of vomiting, abdominal distension and severe growth retardation. Endocrinologic examination indicated growth hormone (GH) secretory dysfunction. Administration of recombinant human GH (rhGH) led to growth, but the patient discontinued treatment. He was readmitted to our hospital in 1993, at the age of 16. His stature was very short. Laboratory findings suggested malnutrition. Radiologic examination revealed regional stenosis and a cobblestone appearance of the intestine. The histologic diagnosis was compatible with Crohn's disease. Administration of prednisolone alleviated gastrointestinal symptoms with the improvement of GH secretory function.

AB - A 10-year-old boy presented in 1989 with repeated episodes of vomiting, abdominal distension and severe growth retardation. Endocrinologic examination indicated growth hormone (GH) secretory dysfunction. Administration of recombinant human GH (rhGH) led to growth, but the patient discontinued treatment. He was readmitted to our hospital in 1993, at the age of 16. His stature was very short. Laboratory findings suggested malnutrition. Radiologic examination revealed regional stenosis and a cobblestone appearance of the intestine. The histologic diagnosis was compatible with Crohn's disease. Administration of prednisolone alleviated gastrointestinal symptoms with the improvement of GH secretory function.

KW - glucocorticoid therapy

KW - neurosecretory dysfunction

KW - pituitary dwarfism

KW - short stature

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Crohn's Disease Associated with Growth Hormone Secretory Dysfunction

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ASJC Scopus subject areas

UN SDG

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