Amphidinin G, a putative biosynthetic precursor of amphidinin A from marine dinoflagellate Amphidinium sp.

Takaaki Kubota, Takahiro Iwai, Haruaki Ishiyama, Kanae Sakai, Tohru Gonoi, Jun'Ichi Kobayashi

研究成果査読

8 被引用数 (Scopus)

抄録

A new linear polyketide, amphidinin G (1), has been isolated from a symbiotic marine dinoflagellate Amphidinium sp. The planar structure of 1 was established mainly based on the 2D NMR data and the stereochemistry was elucidated by the combination of J-value analysis, modified Mosher's method, and NMR chemical shift comparison with synthetic analogues. Amphidinin G (1) was expected to be a biosynthetic precursor of amphidinin A (2), a known linear dinoflagellate polyketide. Amphidinin G (1) showed antifungal activity against Trichophyton mentagrophytes.

本文言語English
ページ(範囲)990-993
ページ数4
ジャーナルTetrahedron Letters
56
8
DOI
出版ステータスPublished - 2月 18 2015
外部発表はい

ASJC Scopus subject areas

  • 生化学
  • 創薬
  • 有機化学

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