抄録
In complement-depleted condition induced by cobra venom factor (CoF, tissue macrophage reaction and macrophage chemotactic activity (MCA) in skin extract from skin lesions induced by DNP-Ascaris extract (DNP-As) were decreased, respectively. MCA in the fraction containing macrophage chemotactic factor b (B fraction) was decreased completely. While MCA in the fraction containing macrophage chemotactic factor a and c (A fraction) was affected only slightly. These results suggested that the decrease of MCA of B-fraction might be associated with depletion of complement system by CoF. Using anti-C5 antibody, it was confirmed that macrophage chemotactic factor-b (MCF-b) (MW 14,000: thermostable) might be derived from C5 fragment in vivo.
| 本文言語 | English |
|---|---|
| ページ（範囲） | 361-367 |
| ページ数 | 7 |
| ジャーナル | International Archives of Allergy and Applied Immunology |
| 巻 | 70 |
| 号 | 4 |
| DOI | |
| 出版ステータス | Published - 1983 |
ASJC Scopus subject areas
- 免疫アレルギー学