がん免疫療法のトランスレーショナルリサーチ

Although a great deal of research on cancer immunotherapy has been conducted using mice, there are many differences between humans and mice, which is associated with some limitations. Therefore, the analysis of human clinical specimens is important for elucidating the essence of cancer immunology. Recently, advances in technology have made it possible to perform comprehensive gene analyses of various clinical specimens. While such analyses are often performed in bulk, we believe that it is important to analyze clinical specimens at the single-cell level in order to understand the role of each cell, including various immune cells, in detail. Various novel findings have been obtained from such analyses.