Hiromichi Dansako

2021

Antiviral mechanism of preclinical antimalarial compounds possessing multiple antiviral activities

Gu, W., Ueda, Y., Dansako, H., Satoh, S. & Kato, N., 5月 2021, In: FASEB BioAdvances. 3, 5, p. 356-373 18 p.

研究成果 › 査読

Open Access

Extracellular vesicles activate ATM-Chk2 signaling pathway through the intercellular transfer of mitochondrial DNA in HBV-infected human hepatocytes

Dansako, H., Ueda, Y., Satoh, S. & Kato, N., 6月 2021, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 35, 6, p. e21680

研究成果 › 査読

3 被引用数 (Scopus)

2020

Identification of ribavirin-responsive cis-elements for GPAM suppression in the GPAM genome

Onomura, D., Satoh, S., Ueda, Y., Dansako, H. & Kato, N., 11月 26 2020, In: Biochemical and Biophysical Research Communications. 533, 1, p. 148-154 7 p.

研究成果 › 査読

Study of multiple genetic variations caused by persistent hepatitis C virus replication in long-term cell culture

Kato, N., Ueda, Y., Sejima, H., Gu, W., Satoh, S., Dansako, H., Ikeda, M. & Shimotohno, K., 2月 2020, In: Archives of Virology. 165, 2, p. 331-343 13 p.

研究成果 › 査読

2 被引用数 (Scopus)

2019

A new hepatoma cell line exhibiting high susceptibility to hepatitis B virus infection

Ueda, Y., Gu, W., Dansako, H., Nishitsuji, H., Satoh, S., Shimotohno, K. & Kato, N., 7月 12 2019, In: Biochemical and Biophysical Research Communications. 515, 1, p. 156-162 7 p.

研究成果 › 査読

2 被引用数 (Scopus)

High-level expression of STING restricts susceptibility to HBV by mediating type III IFN induction

Dansako, H., Imai, H., Ueda, Y., Satoh, S., Shimotohno, K. & Kato, N., 2月 2019, In: FASEB BioAdvances. 1, 2, p. 67-80 14 p.

研究成果 › 査読

Open Access

9 被引用数 (Scopus)

Ribavirin-induced down-regulation of CCAAT/ enhancer-binding protein α leads to suppression of lipogenesis

Satoh, S., Onomura, D., Ueda, Y., Dansako, H., Honda, M., Kaneko, S. & Kato, N., 1月 15 2019, In: Biochemical Journal. 476, 1, p. 137-149 13 p.

研究成果 › 査読

5 被引用数 (Scopus)

2018

Daunorubicin, a topoisomerase II poison, suppresses viral production of hepatitis B virus by inducing cGAS-dependent innate immune response

Imai, H., Dansako, H., Ueda, Y., Satoh, S. & Kato, N., 10月 12 2018, In: Biochemical and Biophysical Research Communications. 504, 4, p. 672-678 7 p.

研究成果 › 査読

11 被引用数 (Scopus)

Multiple antiviral activities of the antimalarial and anti-hepatitis C drug candidates N-89 and N-251

Ueda, Y., Gu, W., Dansako, H., Kim, H. S., Yoshizaki, S., Okumura, N., Ishikawa, T., Nishitsuji, H., Kato, F., Hishiki, T., Satoh, S., Ishii, K., Masuda, M., Shimotohno, K., Ikeda, M. & Kato, N., 9月 2018, In: Biochemistry and Biophysics Reports. 15, p. 1-6 6 p.

研究成果 › 査読

3 被引用数 (Scopus)

ULBP1 is induced by hepatitis C virus infection and is the target of the NK cell-mediated innate immune response in human hepatocytes

Dansako, H., Imai, H., Ueda, Y., Satoh, S., Wakita, T. & Kato, N., 3月 2018, In: FEBS Open Bio. 8, 3, p. 361-371 11 p.

研究成果 › 査読

6 被引用数 (Scopus)

2017

Evaluation of preclinical antimalarial drugs, which can overcome direct-acting antivirals-resistant hepatitis C viruses, using the viral reporter assay systems

Ueda, Y., Dansako, H., Satoh, S., Kim, H-S., Wataya, Y., Doi, H., Ikeda, M. & Kato, N., 5月 2 2017, In: Virus Research. 235, p. 37-48 12 p.

研究成果 › 査読

6 被引用数 (Scopus)

Ribavirin suppresses hepatic lipogenesis through inosine monophosphate dehydrogenase inhibition: Involvement of adenosine monophosphate-activated protein kinase-related kinases and retinoid X receptor α

Satoh, S., Mori, K., Onomura, D., Ueda, Y., Dansako, H., Honda, M., Kaneko, S., Ikeda, M. & Kato, N., 8月 2017, In: Hepatology Communications. 1, 6, p. 550-563 14 p.

研究成果 › 査読

4 被引用数 (Scopus)

2016

Molecular mechanism underlying the suppression of CPB2 expression caused by persistent hepatitis C virus RNA replication

Sejima, H., Satoh, S., Dansako, H., Honda, M., Kaneko, S., Ikeda, M. & Kato, N., 2016, In: Acta Medica Okayama. 70, 2, p. 75-88 14 p.

研究成果 › 査読

1 被引用数 (Scopus)

Rab13 is involved in the entry step of hepatitis C virus infection

Takeda, M., Ikeda, M., Satoh, S., Dansako, H., Wakita, T. & Kato, N., 2016, In: Acta Medica Okayama. 70, 2, p. 111-118 8 p.

研究成果 › 査読

7 被引用数 (Scopus)

The cyclic GMP-AMP synthetase-STING signaling pathway is required for both the innate immune response against HBV and the suppression of HBV assembly

Dansako, H., Ueda, Y., Okumura, N., Satoh, S., Sugiyama, M., Mizokami, M., Ikeda, M. & Kato, N., 1月 1 2016, In: FEBS Journal. 283, 1, p. 144-156 13 p.

研究成果 › 査読

57 被引用数 (Scopus)

2015

Annexin A1 negatively regulates viral RNA replication of hepatitis C virus

Hiramoto, H., Dansako, H., Takeda, M., Satoh, S., Wakita, T., Ikeda, M. & Kato, N., 2015, In: Acta medica Okayama. 69, 2, p. 71-78 8 p.

研究成果 › 査読

9 被引用数 (Scopus)

Establishment of Hepatitis C Virus RNA-Replicating cell lines possessing ribavirin-resistant phenotype

Satoh, S., Mori, K., Ueda, Y., Sejima, H., Dansako, H., Ikeda, M. & Kato, N., 2月 20 2015, In: PLoS One. 10, 2, e0118313.

研究成果 › 査読

6 被引用数 (Scopus)

Negative regulation of hepatitis B virus replication by forkhead box protein A in human hepatoma cells

Okumura, N., Ikeda, M., Satoh, S., Dansako, H., Sugiyama, M., Mizokami, M. & Kato, N., 4月 28 2015, In: FEBS Letters. 589, 10, p. 1112-1118 7 p.

研究成果 › 査読

7 被引用数 (Scopus)

2014

Anti-HCV activity of the Chinese medicinal fungus Cordyceps militaris

Ueda, Y., Mori, K., Satoh, S., Dansako, H., Ikeda, M. & Kato, N., 5月 2 2014, In: Biochemical and Biophysical Research Communications. 447, 2, p. 341-345 5 p.

研究成果 › 査読

21 被引用数 (Scopus)

Genetic characterization of hepatitis C virus in long-term RNA replication using Li23 cell culture systems

Kato, N., Sejima, H., Ueda, Y., Mori, K., Satoh, S., Dansako, H. & Ikeda, M., 3月 13 2014, In: PloS one. 9, 3, e91156.

研究成果 › 査読

10 被引用数 (Scopus)

Rab18 is required for viral assembly of hepatitis C virus through trafficking of the core protein to lipid droplets

Dansako, H., Hiramoto, H., Ikeda, M., Wakita, T. & Kato, N., 8月 2014, In: Virology. 462-463, 1, p. 166-174 9 p.

研究成果 › 査読

39 被引用数 (Scopus)

2013

Class A Scavenger Receptor 1 (MSR1) Restricts Hepatitis C Virus Replication by Mediating Toll-like Receptor 3 Recognition of Viral RNAs Produced in Neighboring Cells

Dansako, H., Yamane, D., Welsch, C., McGivern, D. R., Hu, F., Kato, N. & Lemon, S. M., 5月 2013, In: PLoS Pathogens. 9, 5, e1003345.

研究成果 › 査読

60 被引用数 (Scopus)

New Preclinical Antimalarial Drugs Potently Inhibit Hepatitis C Virus Genotype 1b RNA Replication

Ueda, Y., Takeda, M., Mori, K., Dansako, H., Wakita, T., Kim, H. S., Sato, A., Wataya, Y., Ikeda, M. & Kato, N., 8月 30 2013, In: PloS one. 8, 8, e72519.

研究成果 › 査読

8 被引用数 (Scopus)

PML tumor suppressor protein is required for HCV production

Kuroki, M., Ariumi, Y., Hijikata, M., Ikeda, M., Dansako, H., Wakita, T., Shimotohno, K. & Kato, N., 1月 11 2013, In: Biochemical and Biophysical Research Communications. 430, 2, p. 592-597 6 p.

研究成果 › 査読

10 被引用数 (Scopus)

2012

Development of a drug assay system with hepatitis C virus genome derived from a patient with acute hepatitis C

Mori, K., Ueda, Y., Ariumi, Y., Dansako, H., Ikeda, M. & Kato, N., 6月 2012, In: Virus Genes. 44, 3, p. 374-381 8 p.

研究成果 › 査読

3 被引用数 (Scopus)

Raloxifene inhibits hepatitis C virus infection and replication

Takeda, M., Ikeda, M., Mori, K., Yano, M., Ariumi, Y., Dansako, H., Wakita, T. & Kato, N., 2012, In: FEBS Open Bio. 2, p. 279-283 5 p.

研究成果 › 査読

11 被引用数 (Scopus)

2011

Anti-ulcer agent teprenone inhibits hepatitis C virus replication: Potential treatment for hepatitis C

Ikeda, M., Kawai, Y., Mori, K., Yano, M., Abe, K. I., Nishimura, G., Dansako, H., Ariumi, Y., Wakita, T., Yamamoto, K. & Kato, N., 7月 2011, In: Liver International. 31, 6, p. 871-880 10 p.

研究成果 › 査読

6 被引用数 (Scopus)

Mechanism of action of ribavirin in a novel hepatitis C virus replication cell system

Mori, K., Ikeda, M., Ariumi, Y., Dansako, H., Wakita, T. & Kato, N., 4月 2011, In: Virus research. 157, 1, p. 61-70 10 p.

研究成果 › 査読

47 被引用数 (Scopus)

The ESCRT system is required for hepatitis C virus production

Ariumi, Y., Kuroki, M., Maki, M., Ikeda, M., Dansako, H., Wakita, T. & Kato, N., 2011, In: PloS one. 6, 1, e14517.

研究成果 › 査読

72 被引用数 (Scopus)

2010

Amino acid substitutions of hepatitis C virus core protein are not associated with intracellular antiviral response to interferon-α in vitro

Ikeda, F., Dansako, H., Nishimura, G., Mori, K., Kawai, Y., Ariumi, Y., Miyake, Y., Takaki, A., Nouso, K., Iwasaki, Y., Ikeda, M., Kato, N. & Yamamoto, K., 10月 2010, In: Liver International. 30, 9, p. 1324-1331 8 p.

研究成果 › 査読

9 被引用数 (Scopus)

2009

Arsenic trioxide inhibits hepatitis C Virus RNA replication through modulation of the glutathione redox system and oxidative stress

Kuroki, M., Ariumi, Y., Ikeda, M., Dansako, H., Wakita, T. & Kato, N., 3月 2009, In: Journal of Virology. 83, 5, p. 2338-2348 11 p.

研究成果 › 査読

34 被引用数 (Scopus)

Development of a hepatitis C virus relapse model using genome-length hepatitis C virus ribonucleic acid-harboring cells possessing the interferon-α-resistance phenotype

Kawai, Y., Ikeda, M., Abe, K. I., Yano, M., Ariumi, Y., Dansako, H., Yamamoto, K. & Kato, N., 2009, In: Hepatology Research. 39, 9, p. 898-909 12 p.

研究成果 › 査読

3 被引用数 (Scopus)

Development of an HCV relapse model using genome-length HCV RNA-harboring cells possessing the IFN-a-resistance phenotype.

Dansako, H., 2009, In: Hepatol Res.

研究成果

Double-stranded RNA-induced interferon-beta and inflammatory cytokine production modulated by hepatitis C virus serine proteases derived from patients with hepatic diseases

Dansako, H., Ikeda, M., Ariumi, Y., Wakita, T. & Kato, N., 5月 2009, In: Archives of Virology. 154, 5, p. 801-810 10 p.

研究成果 › 査読

17 被引用数 (Scopus)

Efficient replication systems for hepatitis C virus using a new human hepatoma cell line

Kato, N., Mori, K., Abe, K. I., Dansako, H., Kuroki, M., Ariumi, Y., Wakita, T. & Ikeda, M., 1月 2009, In: Virus research. 146, 1-2, p. 41-50 10 p.

研究成果 › 査読

41 被引用数 (Scopus)

Genetic variability and diversity of intracellular genome-length hepatitis C virus RNA in long-term cell culture

Kato, N., Abe, K., Mori, K., Ariumi, Y., Dansako, H. & Ikeda, M., 1月 2009, In: Archives of Virology. 154, 1, p. 77-85 9 p.

研究成果 › 査読

11 被引用数 (Scopus)

HCV genotype 1b chimeric replicon with NS5B of JFH-1 exhibited resistance to cyclosporine A

Abe, K. I., Ikeda, M., Ariumi, Y., Dansako, H., Wakita, T. & Kato, N., 10月 2009, In: Archives of Virology. 154, 10, p. 1671-1677 7 p.

研究成果 › 査読

10 被引用数 (Scopus)

Oncostatin M synergistically inhibits HCV RNA replication in combination with interferon-α

Ikeda, M., Mori, K., Ariumi, Y., Dansako, H. & Kato, N., 5月 6 2009, In: FEBS Letters. 583, 9, p. 1434-1438 5 p.

研究成果 › 査読

9 被引用数 (Scopus)

Oxidative stress induces anti-hepatitis C virus status via the activation of extracellular signal-regulated kinase

Yano, M., Ikeda, M., Abe, K. I., Kawai, Y., Kuroki, M., Mori, K., Dansako, H., Ariumi, Y., Ohkoshi, S., Aoyagi, Y. & Kato, N., 2009, In: Hepatology. 50, 3, p. 678-688 11 p.

研究成果 › 査読

37 被引用数 (Scopus)

Replicons from genotype 1b HCV-positive sera exhibit diverse sensitivities to anti-HCV reagents

Nishimura, G., Ikeda, M., Mori, K., Nakazawa, T., Ariumi, Y., Dansako, H. & Kato, N., 4月 2009, In: Antiviral Research. 82, 1, p. 42-50 9 p.

研究成果 › 査読

10 被引用数 (Scopus)

2008

A new living cell-based assay system for monitoring genome-length hepatitis C virus RNA replication

Dansako, H., Ikeda, M., Abe, K. I., Mori, K., Takemoto, K., Ariumi, Y. & Kato, N., 10月 2008, In: Virus research. 137, 1, p. 72-79 8 p.

研究成果 › 査読

8 被引用数 (Scopus)

New efficient replication system with hepatitis C virus genome derived from a patient with acute hepatitis C

Mori, K., Abe, K. I., Dansako, H., Ariumi, Y., Ikeda, M. & Kato, N., 6月 20 2008, In: Biochemical and Biophysical Research Communications. 371, 1, p. 104-109 6 p.

研究成果 › 査読

18 被引用数 (Scopus)

The DNA damage sensors ataxia-telangiectasia mutated kinase and checkpoint kinase 2 are required for hepatitis C virus RNA replication

Ariumi, Y., Kuroki, M., Dansako, H., Abe, K. I., Ikeda, M., Wakita, T. & Kato, N., 10月 2008, In: Journal of Virology. 82, 19, p. 9639-9646 8 p.

研究成果 › 査読

57 被引用数 (Scopus)

2007

Cell culture-adaptive NS3 mutations required for the robust replication of genome-length hepatitis C virus RNA

Abe, K. I., Ikeda, M., Dansako, H., Naka, K. & Kato, N., 4月 2007, In: Virus research. 125, 1, p. 88-97 10 p.

研究成果 › 査読

28 被引用数 (Scopus)

Comprehensive analysis of the effects of ordinary nutrients on hepatitis C virus RNA replication in cell culture

Yano, M., Ikeda, M., Abe, K. I., Dansako, H., Ohkoshi, S., Aoyagi, Y. & Kato, N., 6月 2007, In: Antimicrobial Agents and Chemotherapy. 51, 6, p. 2016-2027 12 p.

研究成果 › 査読

73 被引用数 (Scopus)

DDX3 DEAD-box RNA helicase is required for hepatitis C virus RNA replication

Ariumi, Y., Kuroki, M., Abe, K. I., Dansako, H., Ikeda, M., Wakita, T. & Kato, N., 12月 2007, In: Journal of Virology. 81, 24, p. 13922-13926 5 p.

研究成果 › 査読

210 被引用数 (Scopus)

Limited suppression of the interferon-β production by hepatitis C virus serine protease in cultured human hepatocytes

Dansako, H., Ikeda, M. & Kato, N., 8月 2007, In: FEBS Journal. 274, 16, p. 4161-4176 16 p.

研究成果 › 査読

37 被引用数 (Scopus)

Serum-free cell culture system supplemented with lipid-rich albumin for hepatitis C virus (strain O of genotype 1b) replication

Abe, K. I., Ikeda, M., Ariumi, Y., Dansako, H. & Kato, N., 5月 2007, In: Virus research. 125, 2, p. 162-168 7 p.

研究成果 › 査読

3 被引用数 (Scopus)

Tandem repeats of lactoferrin-derived anti-hepatitis C virus peptide enhance antiviral activity in cultured human hepatocytes

Abe, K. I., Nozaki, A., Tamura, K., Ikeda, M., Naka, K., Dansako, H., Hoshino, H. O., Tanaka, K. & Kato, N., 2007, In: MICROBIOLOGY and IMMUNOLOGY. 51, 1, p. 117-125 9 p.

研究成果 › 査読

20 被引用数 (Scopus)

2006

Different anti-HCV profiles of statins and their potential for combination therapy with interferon

Ikeda, M., Abe, K. I., Yamada, M., Dansako, H., Naka, K. & Kato, N., 7月 2006, In: Hepatology. 44, 1, p. 117-125 9 p.

研究成果 › 査読

260 被引用数 (Scopus)

Hiromichi Dansako

研究成果

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