Zamamiphidin A, a new manzamine related alkaloid from an Okinawan marine sponge amphimedon sp.

Takaaki Kubota, Yuki Kamijyo, Azusa Takahashi-Nakaguchi, Jane Fromont, Tohru Gonoi, Jun'Ichi Kobayashi

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)

Abstract

A manzamine related alkaloid, zamamiphidin A (1), consisting of a new heptacyclic ring system has been isolated from an Okinawan marine sponge Amphimedon sp. The structure of 1 including the relative stereochemistry was elucidated on the basis of the spectroscopic data. Compound 1 showed antibacterial activity against Staphylococcus aureus (MIC, 32 μg/mL).

Original languageEnglish
Pages (from-to)610-612
Number of pages3
JournalOrganic Letters
Volume15
Issue number3
DOIs
Publication statusPublished - Feb 1 2013
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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