Zamamiphidin A, a new manzamine related alkaloid from an Okinawan marine sponge amphimedon sp.

Takaaki Kubota; Yuki Kamijyo; Azusa Takahashi-Nakaguchi; Jane Fromont; Tohru Gonoi; Jun'Ichi Kobayashi

doi:10.1021/ol3034274

Zamamiphidin A, a new manzamine related alkaloid from an Okinawan marine sponge amphimedon sp.

Takaaki Kubota, Yuki Kamijyo, Azusa Takahashi-Nakaguchi, Jane Fromont, Tohru Gonoi, Jun'Ichi Kobayashi

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Abstract

A manzamine related alkaloid, zamamiphidin A (1), consisting of a new heptacyclic ring system has been isolated from an Okinawan marine sponge Amphimedon sp. The structure of 1 including the relative stereochemistry was elucidated on the basis of the spectroscopic data. Compound 1 showed antibacterial activity against Staphylococcus aureus (MIC, 32 μg/mL).

Original language	English
Pages (from-to)	610-612
Number of pages	3
Journal	Organic Letters
Volume	15
Issue number	3
DOIs	https://doi.org/10.1021/ol3034274
Publication status	Published - Feb 1 2013
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1021/ol3034274

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abstract = "A manzamine related alkaloid, zamamiphidin A (1), consisting of a new heptacyclic ring system has been isolated from an Okinawan marine sponge Amphimedon sp. The structure of 1 including the relative stereochemistry was elucidated on the basis of the spectroscopic data. Compound 1 showed antibacterial activity against Staphylococcus aureus (MIC, 32 μg/mL).",

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AU - Kubota, Takaaki

AU - Kamijyo, Yuki

AU - Takahashi-Nakaguchi, Azusa

AU - Fromont, Jane

AU - Gonoi, Tohru

AU - Kobayashi, Jun'Ichi

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AB - A manzamine related alkaloid, zamamiphidin A (1), consisting of a new heptacyclic ring system has been isolated from an Okinawan marine sponge Amphimedon sp. The structure of 1 including the relative stereochemistry was elucidated on the basis of the spectroscopic data. Compound 1 showed antibacterial activity against Staphylococcus aureus (MIC, 32 μg/mL).

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Zamamiphidin A, a new manzamine related alkaloid from an Okinawan marine sponge amphimedon sp.

Abstract

ASJC Scopus subject areas

UN SDGs

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