Zamamidines A and B, new manzamine alkaloids from the sponge Amphimedon species

Yohei Takahashi, Takaaki Kubota, Jane Fromont, Jun'ichi Kobayashi

Research output: Contribution to journalArticlepeer-review

29 Citations (Scopus)

Abstract

New manzamine alkaloids, zamamidines A (1) and B (2), have been isolated from an Okinawan marine sponge Amphimedon species. The structures and stereochemistry of 1 and 2 were elucidated from the spectroscopic data and conformational analysis. Zamamidines A (1) and B (2) are the first manzamine alkaloids possessing a second //-carboline ring via an ethylene unit at N-2 of manzamine H and 1,2,3,4-tetrahydromanzamine B, respectively.

Original languageEnglish
Pages (from-to)21-24
Number of pages4
JournalOrganic Letters
Volume11
Issue number1
DOIs
Publication statusPublished - Jan 1 2009
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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