Xylomexicanins C and D, new mexicanolide-type limonoids from xylocarpus granatum

Yi Bing Wu; Zhi Yu Ni; Chang Hong Huo; Jian Su; Mei Dong; Françoise Sauriol; Qing Wen Shi; Yu Cheng Gu; Hiromasa Kiyota

doi:10.1271/bbb.120815

Xylomexicanins C and D, new mexicanolide-type limonoids from xylocarpus granatum

Yi Bing Wu, Zhi Yu Ni, Chang Hong Huo, Jian Su, Mei Dong, Françoise Sauriol, Qing Wen Shi, Yu Cheng Gu, Hiromasa Kiyota

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Abstract

Two new limonoids, named xylomexicanins C and D, were isolated from a dichloromethane extract of the seeds of Xylocarpus granatum cultivated in Hainan, China, and their structures were elucidated on the basis of one- and two-dimensional NMR (including ¹H, ¹³CNMR, DEPT, ¹H-¹H COSY, HSQC, HMBC, and NOESY) and confirmed by high-resolution mass spectrometry. Xylomexicanin C exhibited antiproliferative activity against human breast carcinoma cells (KT).

Original language	English
Pages (from-to)	736-740
Number of pages	5
Journal	Bioscience, Biotechnology and Biochemistry
Volume	77
Issue number	4
DOIs	https://doi.org/10.1271/bbb.120815
Publication status	Published - 2013
Externally published	Yes

Keywords

Limonoid
Mexicanolide
NMR
Structural elucidation
Xylocarpus granatum

ASJC Scopus subject areas

Biotechnology
Analytical Chemistry
Biochemistry
Applied Microbiology and Biotechnology
Molecular Biology
Organic Chemistry

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10.1271/bbb.120815

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title = "Xylomexicanins C and D, new mexicanolide-type limonoids from xylocarpus granatum",

abstract = "Two new limonoids, named xylomexicanins C and D, were isolated from a dichloromethane extract of the seeds of Xylocarpus granatum cultivated in Hainan, China, and their structures were elucidated on the basis of one- and two-dimensional NMR (including 1H, 13CNMR, DEPT, 1H-1H COSY, HSQC, HMBC, and NOESY) and confirmed by high-resolution mass spectrometry. Xylomexicanin C exhibited antiproliferative activity against human breast carcinoma cells (KT).",

keywords = "Limonoid, Mexicanolide, NMR, Structural elucidation, Xylocarpus granatum",

author = "Wu, {Yi Bing} and Ni, {Zhi Yu} and Huo, {Chang Hong} and Jian Su and Mei Dong and Fran{\c c}oise Sauriol and Shi, {Qing Wen} and Gu, {Yu Cheng} and Hiromasa Kiyota",

note = "Funding Information: We are grateful for the financial support from National Natural Science Foundation of China (81072551 and 81241101), Key Projects of Science and Technology of Hebei Province (11276103D-89), and Scientific Research Foundation of Hebei Province (C2010000489). We also give our sincere thanks for the financial support from Syngenta Ltd. (2011-Hebei Medical University-Syngenta-03) and JSPS Kakenhi Grant 22580112.",

year = "2013",

doi = "10.1271/bbb.120815",

language = "English",

volume = "77",

pages = "736--740",

journal = "Bioscience, Biotechnology and Biochemistry",

issn = "0916-8451",

publisher = "Japan Society for Bioscience Biotechnology and Agrochemistry",

number = "4",

}

TY - JOUR

T1 - Xylomexicanins C and D, new mexicanolide-type limonoids from xylocarpus granatum

AU - Wu, Yi Bing

AU - Ni, Zhi Yu

AU - Huo, Chang Hong

AU - Su, Jian

AU - Dong, Mei

AU - Sauriol, Françoise

AU - Shi, Qing Wen

AU - Gu, Yu Cheng

AU - Kiyota, Hiromasa

N1 - Funding Information: We are grateful for the financial support from National Natural Science Foundation of China (81072551 and 81241101), Key Projects of Science and Technology of Hebei Province (11276103D-89), and Scientific Research Foundation of Hebei Province (C2010000489). We also give our sincere thanks for the financial support from Syngenta Ltd. (2011-Hebei Medical University-Syngenta-03) and JSPS Kakenhi Grant 22580112.

PY - 2013

Y1 - 2013

N2 - Two new limonoids, named xylomexicanins C and D, were isolated from a dichloromethane extract of the seeds of Xylocarpus granatum cultivated in Hainan, China, and their structures were elucidated on the basis of one- and two-dimensional NMR (including 1H, 13CNMR, DEPT, 1H-1H COSY, HSQC, HMBC, and NOESY) and confirmed by high-resolution mass spectrometry. Xylomexicanin C exhibited antiproliferative activity against human breast carcinoma cells (KT).

AB - Two new limonoids, named xylomexicanins C and D, were isolated from a dichloromethane extract of the seeds of Xylocarpus granatum cultivated in Hainan, China, and their structures were elucidated on the basis of one- and two-dimensional NMR (including 1H, 13CNMR, DEPT, 1H-1H COSY, HSQC, HMBC, and NOESY) and confirmed by high-resolution mass spectrometry. Xylomexicanin C exhibited antiproliferative activity against human breast carcinoma cells (KT).

KW - Limonoid

KW - Mexicanolide

KW - NMR

KW - Structural elucidation

KW - Xylocarpus granatum

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DO - 10.1271/bbb.120815

M3 - Article

C2 - 23563540

AN - SCOPUS:84878812587

SN - 0916-8451

VL - 77

SP - 736

EP - 740

JO - Bioscience, Biotechnology and Biochemistry

JF - Bioscience, Biotechnology and Biochemistry

IS - 4

ER -

Xylomexicanins C and D, new mexicanolide-type limonoids from xylocarpus granatum

Abstract

Keywords

ASJC Scopus subject areas

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