Xylomexicanins C and D, new mexicanolide-type limonoids from xylocarpus granatum

Yi Bing Wu, Zhi Yu Ni, Chang Hong Huo, Jian Su, Mei Dong, Françoise Sauriol, Qing Wen Shi, Yu Cheng Gu, Hiromasa Kiyota

Research output: Contribution to journalArticle

13 Citations (Scopus)


Two new limonoids, named xylomexicanins C and D, were isolated from a dichloromethane extract of the seeds of Xylocarpus granatum cultivated in Hainan, China, and their structures were elucidated on the basis of one- and two-dimensional NMR (including 1H, 13CNMR, DEPT, 1H-1H COSY, HSQC, HMBC, and NOESY) and confirmed by high-resolution mass spectrometry. Xylomexicanin C exhibited antiproliferative activity against human breast carcinoma cells (KT).

Original languageEnglish
Pages (from-to)736-740
Number of pages5
JournalBioscience, Biotechnology and Biochemistry
Issue number4
Publication statusPublished - Jun 14 2013
Externally publishedYes



  • Limonoid
  • Mexicanolide
  • NMR
  • Structural elucidation
  • Xylocarpus granatum

ASJC Scopus subject areas

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

Cite this

Wu, Y. B., Ni, Z. Y., Huo, C. H., Su, J., Dong, M., Sauriol, F., Shi, Q. W., Gu, Y. C., & Kiyota, H. (2013). Xylomexicanins C and D, new mexicanolide-type limonoids from xylocarpus granatum. Bioscience, Biotechnology and Biochemistry, 77(4), 736-740. https://doi.org/10.1271/bbb.120815