Xylomexicanins A and B, New Δ14,15-Mexicanolides from Seeds of the Chinese Mangrove Xylocarpus granatum

Li Ru Shen; Bao Wei Yin; Man Li Zhang; Qing Wen Shi; Chang Hong Huo; Mei Dong; Bin Cong; Dong Guo; Hiromasa Kiyota; Nobuo Suzuki

doi:10.1515/znc-2009-1-207

Xylomexicanins A and B, New Δ^14,15-Mexicanolides from Seeds of the Chinese Mangrove Xylocarpus granatum

Li Ru Shen, Bao Wei Yin, Man Li Zhang, Qing Wen Shi, Chang Hong Huo, Mei Dong, Bin Cong, Dong Guo, Hiromasa Kiyota, Nobuo Suzuki

Research output: Contribution to journal › Article › peer-review

29 Citations (Scopus)

Abstract

Two new mexicanolide-type limonoids, named xylomexicanin A (1) and xylomexicanin B (2), were isolated from seeds of the Chinese mangrove Xylocarpus granatum. Their structures were elucidated on the basis of spectroscopic methods. Compound 1 exhibited antipro-liferative activity against human breast carcinoma cells (KT), while 2 did not show inhibitory effects on eleven human tumour cell lines tested.

Original language	English
Pages (from-to)	37-42
Number of pages	6
Journal	Zeitschrift fur Naturforschung - Section C Journal of Biosciences
Volume	64
Issue number	1-2
DOIs	https://doi.org/10.1515/znc-2009-1-207
Publication status	Published - Jan 2009
Externally published	Yes

Keywords

Antiproliferative Activity
Limonoids
Xylocarpus granatum

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

Access to Document

10.1515/znc-2009-1-207

Cite this

@article{59a314c3d348430f9ab5caf68b408a40,

title = "Xylomexicanins A and B, New Δ14,15-Mexicanolides from Seeds of the Chinese Mangrove Xylocarpus granatum",

abstract = "Two new mexicanolide-type limonoids, named xylomexicanin A (1) and xylomexicanin B (2), were isolated from seeds of the Chinese mangrove Xylocarpus granatum. Their structures were elucidated on the basis of spectroscopic methods. Compound 1 exhibited antipro-liferative activity against human breast carcinoma cells (KT), while 2 did not show inhibitory effects on eleven human tumour cell lines tested.",

keywords = "Antiproliferative Activity, Limonoids, Xylocarpus granatum",

author = "Shen, {Li Ru} and Yin, {Bao Wei} and Zhang, {Man Li} and Shi, {Qing Wen} and Huo, {Chang Hong} and Mei Dong and Bin Cong and Dong Guo and Hiromasa Kiyota and Nobuo Suzuki",

note = "Funding Information: This work was supported by the Science Foundation of Hebei Medical University, Department of Education, Hebei Province, China (2006129), China Postdoctoral Science Foundation (20070410869), and a grant-in-aid from Japan Society for the Promotion of Science (No. 19580120).",

year = "2009",

month = jan,

doi = "10.1515/znc-2009-1-207",

language = "English",

volume = "64",

pages = "37--42",

journal = "Zeitschrift fur Naturforschung. Teil C: Biochemie, Biophysik, Biologie, Virologie",

issn = "0939-5075",

publisher = "Verlag der Zeitschrift fur Naturforschung",

number = "1-2",

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T1 - Xylomexicanins A and B, New Δ14,15-Mexicanolides from Seeds of the Chinese Mangrove Xylocarpus granatum

AU - Shen, Li Ru

AU - Yin, Bao Wei

AU - Zhang, Man Li

AU - Shi, Qing Wen

AU - Huo, Chang Hong

AU - Dong, Mei

AU - Cong, Bin

AU - Guo, Dong

AU - Kiyota, Hiromasa

AU - Suzuki, Nobuo

N1 - Funding Information: This work was supported by the Science Foundation of Hebei Medical University, Department of Education, Hebei Province, China (2006129), China Postdoctoral Science Foundation (20070410869), and a grant-in-aid from Japan Society for the Promotion of Science (No. 19580120).

PY - 2009/1

Y1 - 2009/1

N2 - Two new mexicanolide-type limonoids, named xylomexicanin A (1) and xylomexicanin B (2), were isolated from seeds of the Chinese mangrove Xylocarpus granatum. Their structures were elucidated on the basis of spectroscopic methods. Compound 1 exhibited antipro-liferative activity against human breast carcinoma cells (KT), while 2 did not show inhibitory effects on eleven human tumour cell lines tested.

AB - Two new mexicanolide-type limonoids, named xylomexicanin A (1) and xylomexicanin B (2), were isolated from seeds of the Chinese mangrove Xylocarpus granatum. Their structures were elucidated on the basis of spectroscopic methods. Compound 1 exhibited antipro-liferative activity against human breast carcinoma cells (KT), while 2 did not show inhibitory effects on eleven human tumour cell lines tested.

KW - Antiproliferative Activity

KW - Limonoids

KW - Xylocarpus granatum

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