Worsened long-term outcomes and postoperative complications in octogenarians with lung cancer following mediastinal lymph-node dissection

Masayuki Chida, Muneo Minowa, Yoko Karube, Syunsuke Eba, Yoshinori Okada, Shinichiro Miyoshi, Takashi Kondo

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

We evaluated the effects of mediastinal lymph-node dissection on outcomes in octogenarians with primary lung cancer. Outcomes and postoperative complications were retrospectively investigated in 48 octogenarians with anatomically resected lung cancer, of whom 23 underwent a mediastinal lymph-node dissection (ND2 group) and 25 a limited lymphadenectomy (ND0-1 group). Forty-three patients underwent a lobectomy, two a pneumonectomy, and three a segmentectomy. The five-year survival rate for all was 35%, while that for those in pathological stage I was 43.3% and for those in stage II + III was 21.2%. As for lymph node dissection, the five-year survival rate for the ND0-1 group (54.3%) was superior to that for the ND2 group (21.7%) (P=0.022). For patients in pathological stage I, those rated ND0-1 had a better five-year survival than those rated ND2 (61.9% vs. 28.6%) (P=0.041). In addition, mediastinal lymph-node dissection increased the incidence of postoperative cardiac complications (P=0.004). Our results indicate that major pulmonary resection with mediastinal lymph-node dissection is associated with a higher rate of mortality in octogenarians with lung cancer.

Original languageEnglish
Pages (from-to)89-92
Number of pages4
JournalInteractive Cardiovascular and Thoracic Surgery
Volume8
Issue number1
DOIs
Publication statusPublished - Jan 2009
Externally publishedYes

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Lymph Node Excision
Lung Neoplasms
Survival Rate
Segmental Mastectomy
Pneumonectomy
Lung
Survival
Mortality
Incidence

Keywords

  • Complication
  • Elderly
  • Lung cancer
  • Octogenarian

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Pulmonary and Respiratory Medicine
  • Surgery

Cite this

Worsened long-term outcomes and postoperative complications in octogenarians with lung cancer following mediastinal lymph-node dissection. / Chida, Masayuki; Minowa, Muneo; Karube, Yoko; Eba, Syunsuke; Okada, Yoshinori; Miyoshi, Shinichiro; Kondo, Takashi.

In: Interactive Cardiovascular and Thoracic Surgery, Vol. 8, No. 1, 01.2009, p. 89-92.

Research output: Contribution to journalArticle

Chida, Masayuki ; Minowa, Muneo ; Karube, Yoko ; Eba, Syunsuke ; Okada, Yoshinori ; Miyoshi, Shinichiro ; Kondo, Takashi. / Worsened long-term outcomes and postoperative complications in octogenarians with lung cancer following mediastinal lymph-node dissection. In: Interactive Cardiovascular and Thoracic Surgery. 2009 ; Vol. 8, No. 1. pp. 89-92.
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