Visualisation method of spatial interictal discharges in temporal epilepsy patients using magneto-encephalogram

A. Kandori, H. Oe, K. Miyashita, H. Date, N. Yamada, H. Naritomi, Y. Chiba, M. Murakami, T. Miyashita, K. Tsukada

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The aim of the study was to develop a method for investigating how interictal epileptic discharges in temporal epilepsy patients are activated spatially. The activity was measured using magneto-encephalography (MEG). The MEG data were used to produce a current-arrow map that reflected the topographic distribution of the electrical current for each peak epileptic waveform. A large current distribution was obtained that appeared to be contained in the limbic structure, in each temporal lobe. The large current orientation indicated two opposite directions. Furthermore, the decrease in the maximum strength of the current-arrow, depending on the medication (e.g. the decrease from 11 to 6pT m-1 in the left temporal lobe (contralateral stimuli)), suggested that the discharge distributions could be used to verify the efficacy of medication. Thus the topographical visualisation method could be a new strategy for diagnosis in temporal epilepsy patients.

Original languageEnglish
Pages (from-to)327-331
Number of pages5
JournalMedical and Biological Engineering and Computing
Volume40
Issue number3
DOIs
Publication statusPublished - Jan 1 2002
Externally publishedYes

Keywords

  • Current-arrow map
  • Interictal discharge
  • Kindling phenomenon
  • Limbic structure
  • Magneto-encephalogram
  • Temporal epilepsy

ASJC Scopus subject areas

  • Biomedical Engineering
  • Computer Science Applications

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  • Cite this

    Kandori, A., Oe, H., Miyashita, K., Date, H., Yamada, N., Naritomi, H., Chiba, Y., Murakami, M., Miyashita, T., & Tsukada, K. (2002). Visualisation method of spatial interictal discharges in temporal epilepsy patients using magneto-encephalogram. Medical and Biological Engineering and Computing, 40(3), 327-331. https://doi.org/10.1007/BF02344215