Verification of implant surface modification by a novel processing method

Yoshiki Okada, Nobuhiro Abe, Noriyuki Hisamori, Toshiaki Kaneeda, Shigeaki Moriyama, Hitoshi Ohmori, Masayoshi Mizutani, Hiroyuki Yanai, Yoshio Nakashima, Yusuke Yokoyama, Toshihumi Ozaki

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Metals have been used clinically as biomaterials, especially in the orthopaedic and dental fields. Metals used as implants wear at contact surfaces, producing metal particles and metal ions that may be harmful. Newly developed metal implants and methods of implant surface modification are currently under scrutiny. We evaluated the use of electrolytic in-process dressing (ELID) as a surface finishing method for metal implants. Metal implants processed using the ELID method (ELID group) or not processed (Non-ELID group) were inserted surgically into rabbit femurs. The rabbits were sacrificed postoperatively over a 24-week period. We assessed the concentrations of the cytokines, interleukin (IL)-1ß, IL-6, and tumor necrosis factor-α, the resistance to implant pull-out, and histopathology at the implant site. There was no significant difference between the groups regarding the cytokine concentrations or implant pull-out resistance. Many particles indicating wear around the implant were noted in the Non-ELID group (n=10) but not the ELID group (n=13), while a fibrous membrane adhering to the every implant was noted in the ELID group. The formation of a fibrous membrane rather than metal particles in the ELID group may indicate improved biocompatibility, and it suggests that ELID may prevent corrosion in the areas of contact.

Original languageEnglish
Pages (from-to)49-57
Number of pages9
JournalActa Medica Okayama
Volume71
Issue number1
Publication statusPublished - 2017

Fingerprint

Bandages
Surface treatment
Group Processes
Fibrous membranes
Metals
Processing
Wear of materials
Cytokines
Orthopedics
Biocompatible Materials
Interleukin-1
Biocompatibility
Metal ions
Interleukin-6
Tumor Necrosis Factor-alpha
Corrosion
Rabbits
Membranes
Metal implants
Femur

Keywords

  • Biomaterial
  • Metal implant
  • Metal ion
  • Surface modification
  • Wear

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Okada, Y., Abe, N., Hisamori, N., Kaneeda, T., Moriyama, S., Ohmori, H., ... Ozaki, T. (2017). Verification of implant surface modification by a novel processing method. Acta Medica Okayama, 71(1), 49-57.

Verification of implant surface modification by a novel processing method. / Okada, Yoshiki; Abe, Nobuhiro; Hisamori, Noriyuki; Kaneeda, Toshiaki; Moriyama, Shigeaki; Ohmori, Hitoshi; Mizutani, Masayoshi; Yanai, Hiroyuki; Nakashima, Yoshio; Yokoyama, Yusuke; Ozaki, Toshihumi.

In: Acta Medica Okayama, Vol. 71, No. 1, 2017, p. 49-57.

Research output: Contribution to journalArticle

Okada, Y, Abe, N, Hisamori, N, Kaneeda, T, Moriyama, S, Ohmori, H, Mizutani, M, Yanai, H, Nakashima, Y, Yokoyama, Y & Ozaki, T 2017, 'Verification of implant surface modification by a novel processing method', Acta Medica Okayama, vol. 71, no. 1, pp. 49-57.
Okada Y, Abe N, Hisamori N, Kaneeda T, Moriyama S, Ohmori H et al. Verification of implant surface modification by a novel processing method. Acta Medica Okayama. 2017;71(1):49-57.
Okada, Yoshiki ; Abe, Nobuhiro ; Hisamori, Noriyuki ; Kaneeda, Toshiaki ; Moriyama, Shigeaki ; Ohmori, Hitoshi ; Mizutani, Masayoshi ; Yanai, Hiroyuki ; Nakashima, Yoshio ; Yokoyama, Yusuke ; Ozaki, Toshihumi. / Verification of implant surface modification by a novel processing method. In: Acta Medica Okayama. 2017 ; Vol. 71, No. 1. pp. 49-57.
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