Abstract
Two patients with methicillin-resistant Staphylococcus aureus (MRSA) infection were treated with vancomycin (VCM)-impregnated polymethylmethacrylate (PMMA) beads. One patient, who had a history of polycystic kidney and diabetes mellitus, who was receiving hemodialysis due because of non-functional kidney, underwent resection of an intermediate grade chondrosarcoma in the pelvis. MRSA infection developed and curettage of the lesion was performed, but MRSA infection recurred. During the second revision surgery, VCM-impregnated PMMA beads were implanted. MRSA infection has not recurred for 16 months since the implantation of the VCM beads. The second patient had a history of total hip arthroplasty (THA) performed because of coxarthrosis. After the initial surgery, MRSA infection developed, recurring after the second revision surgery for THA. After curettage following removal of the prosthesis, VCM beads were implanted with a spacer composed of VCM-PMMA and a Luque rod. Infection did not recur and THA revision was performed 3 months after the VCM beads implantation. Fifteen months after the last revision surgery, infection has not recurred.
| Original language | English |
|---|---|
| Pages (from-to) | 163-168 |
| Number of pages | 6 |
| Journal | Journal of Orthopaedic Science |
| Volume | 3 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 1998 |
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Keywords
- Beads
- Infection
- Methicillin-resistant Staphylococcus aureus (MRSA)
- Polymethylmethacrylate (PMMA)
- Vancomycin
ASJC Scopus subject areas
- Surgery
Cite this
Vancomycin-impregnated polymethylmethacrylate beads for methicillin- resistant Staphylococcus aureus (MRSA) infection : Report of two cases. / Ozaki, Toshihumi; Yoshitaka, Teruhito; Kunisada, Toshiyuki; Dan'ura, Tomoyuki; Naito, Noriko; Inoue, Hajime.
In: Journal of Orthopaedic Science, Vol. 3, No. 3, 1998, p. 163-168.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Vancomycin-impregnated polymethylmethacrylate beads for methicillin- resistant Staphylococcus aureus (MRSA) infection
T2 - Report of two cases
AU - Ozaki, Toshihumi
AU - Yoshitaka, Teruhito
AU - Kunisada, Toshiyuki
AU - Dan'ura, Tomoyuki
AU - Naito, Noriko
AU - Inoue, Hajime
PY - 1998
Y1 - 1998
N2 - Two patients with methicillin-resistant Staphylococcus aureus (MRSA) infection were treated with vancomycin (VCM)-impregnated polymethylmethacrylate (PMMA) beads. One patient, who had a history of polycystic kidney and diabetes mellitus, who was receiving hemodialysis due because of non-functional kidney, underwent resection of an intermediate grade chondrosarcoma in the pelvis. MRSA infection developed and curettage of the lesion was performed, but MRSA infection recurred. During the second revision surgery, VCM-impregnated PMMA beads were implanted. MRSA infection has not recurred for 16 months since the implantation of the VCM beads. The second patient had a history of total hip arthroplasty (THA) performed because of coxarthrosis. After the initial surgery, MRSA infection developed, recurring after the second revision surgery for THA. After curettage following removal of the prosthesis, VCM beads were implanted with a spacer composed of VCM-PMMA and a Luque rod. Infection did not recur and THA revision was performed 3 months after the VCM beads implantation. Fifteen months after the last revision surgery, infection has not recurred.
AB - Two patients with methicillin-resistant Staphylococcus aureus (MRSA) infection were treated with vancomycin (VCM)-impregnated polymethylmethacrylate (PMMA) beads. One patient, who had a history of polycystic kidney and diabetes mellitus, who was receiving hemodialysis due because of non-functional kidney, underwent resection of an intermediate grade chondrosarcoma in the pelvis. MRSA infection developed and curettage of the lesion was performed, but MRSA infection recurred. During the second revision surgery, VCM-impregnated PMMA beads were implanted. MRSA infection has not recurred for 16 months since the implantation of the VCM beads. The second patient had a history of total hip arthroplasty (THA) performed because of coxarthrosis. After the initial surgery, MRSA infection developed, recurring after the second revision surgery for THA. After curettage following removal of the prosthesis, VCM beads were implanted with a spacer composed of VCM-PMMA and a Luque rod. Infection did not recur and THA revision was performed 3 months after the VCM beads implantation. Fifteen months after the last revision surgery, infection has not recurred.
KW - Beads
KW - Infection
KW - Methicillin-resistant Staphylococcus aureus (MRSA)
KW - Polymethylmethacrylate (PMMA)
KW - Vancomycin
UR - http://www.scopus.com/inward/record.url?scp=0031808003&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0031808003&partnerID=8YFLogxK
U2 - 10.1007/s007760050037
DO - 10.1007/s007760050037
M3 - Article
C2 - 9683770
AN - SCOPUS:0031808003
VL - 3
SP - 163
EP - 168
JO - Journal of Orthopaedic Science
JF - Journal of Orthopaedic Science
SN - 0949-2658
IS - 3
ER -