TY - JOUR
T1 - Validity of a New Kit Measuring Salivary Lactate Dehydrogenase Level for Screening Gingivitis
AU - Ekuni, Daisuke
AU - Yamane-Takeuchi, Mayu
AU - Kataoka, Kota
AU - Yokoi, Aya
AU - Tabata, Ayano
AU - Mizuno, Hirofumi
AU - Miyai, Hisataka
AU - Uchida, Yoko
AU - Fukuhara, Daiki
AU - Sugiura, Yoshio
AU - Tomofuji, Takaaki
AU - Morita, Manabu
N1 - Publisher Copyright:
© 2017 Daisuke Ekuni et al.
PY - 2017
Y1 - 2017
N2 - Aim. The aim of this study was to determine the usefulness of a new kit that can evaluate salivary lactate dehydrogenase (LD) level in real time for screening gingivitis. Materials and Methods. The study included 70 systemic healthy volunteers [29 males and 41 females; mean age ± SD: 24.1 ± 2.6 years]. Resting saliva was collected from each participant and LD level was evaluated in real time using the kit (a color-changing sheet with an integer scale ranging from 1 to 10). A dentist measured probing pocket depth, clinical attachment level, and the proportion of sites with bleeding on probing (% BOP) at six sites on all teeth. Gingivitis was diagnosed when the BOP value was ≥20%. Results. Salivary LD level was positively correlated with mean % BOP (odds ratio: 1.47, 95% confidence interval: 1.132-1.916, and P < 0.001) in a logistic regression model. The sensitivity and specificity of the kit were 0.89 and 0.98, respectively, at a cut-off value of 8.0 for LD level. Conclusions. The new kit for measurement of salivary LD level may be a useful tool to screen for gingivitis in young adults, which contributes to early detection of future periodontitis.
AB - Aim. The aim of this study was to determine the usefulness of a new kit that can evaluate salivary lactate dehydrogenase (LD) level in real time for screening gingivitis. Materials and Methods. The study included 70 systemic healthy volunteers [29 males and 41 females; mean age ± SD: 24.1 ± 2.6 years]. Resting saliva was collected from each participant and LD level was evaluated in real time using the kit (a color-changing sheet with an integer scale ranging from 1 to 10). A dentist measured probing pocket depth, clinical attachment level, and the proportion of sites with bleeding on probing (% BOP) at six sites on all teeth. Gingivitis was diagnosed when the BOP value was ≥20%. Results. Salivary LD level was positively correlated with mean % BOP (odds ratio: 1.47, 95% confidence interval: 1.132-1.916, and P < 0.001) in a logistic regression model. The sensitivity and specificity of the kit were 0.89 and 0.98, respectively, at a cut-off value of 8.0 for LD level. Conclusions. The new kit for measurement of salivary LD level may be a useful tool to screen for gingivitis in young adults, which contributes to early detection of future periodontitis.
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U2 - 10.1155/2017/9547956
DO - 10.1155/2017/9547956
M3 - Article
C2 - 28337048
AN - SCOPUS:85015736721
VL - 2017
JO - Disease Markers
JF - Disease Markers
SN - 0278-0240
M1 - 9547956
ER -