Using the Acropora digitifera genome to understand coral responses to environmental change

Chuya Shinzato, Eiichi Shoguchi, Takeshi Kawashima, Mayuko Hamada, Kanako Hisata, Makiko Tanaka, Manabu Fujie, Mayuki Fujiwara, Ryo Koyanagi, Tetsuro Ikuta, Asao Fujiyama, David J. Miller, Nori Satoh

Research output: Contribution to journalArticle

421 Citations (Scopus)

Abstract

Despite the enormous ecological and economic importance of coral reefs, the keystone organisms in their establishment, the scleractinian corals, increasingly face a range of anthropogenic challenges including ocean acidification and seawater temperature rise. To understand better the molecular mechanisms underlying coral biology, here we decoded the approximately 420-megabase genome of Acropora digitifera using next-generation sequencing technology. This genome contains approximately 23,700 gene models. Molecular phylogenetics indicate that the coral and the sea anemone Nematostella vectensis diverged approximately 500 million years ago, considerably earlier than the time over which modern corals are represented in the fossil record (1/4240 million years ago). Despite the long evolutionary history of the endosymbiosis, no evidence was found for horizontal transfer of genes from symbiont to host. However, unlike several other corals, Acropora seems to lack an enzyme essential for cysteine biosynthesis, implying dependency of this coral on its symbionts for this amino acid. Corals inhabit environments where they are frequently exposed to high levels of solar radiation, and analysis of the Acropora genome data indicates that the coral host can independently carry out de novo synthesis of mycosporine-like amino acids, which are potent ultraviolet-protective compounds. In addition, the coral innate immunity repertoire is notably more complex than that of the sea anemone, indicating that some of these genes may have roles in symbiosis or coloniality. A number of genes with putative roles in calcification were identified, and several of these are restricted to corals. The coral genome provides a platform for understanding the molecular basis of symbiosis and responses to environmental changes.

Original languageEnglish
Pages (from-to)320-323
Number of pages4
JournalNature
Volume476
Issue number7360
DOIs
Publication statusPublished - Aug 18 2011
Externally publishedYes

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Anthozoa
Genome
Symbiosis
Sea Anemones
Coral Reefs
Genes
Amino Acids
Horizontal Gene Transfer
Seawater
Innate Immunity
Oceans and Seas
Cysteine
History
Economics
Radiation

ASJC Scopus subject areas

  • General

Cite this

Shinzato, C., Shoguchi, E., Kawashima, T., Hamada, M., Hisata, K., Tanaka, M., ... Satoh, N. (2011). Using the Acropora digitifera genome to understand coral responses to environmental change. Nature, 476(7360), 320-323. https://doi.org/10.1038/nature10249

Using the Acropora digitifera genome to understand coral responses to environmental change. / Shinzato, Chuya; Shoguchi, Eiichi; Kawashima, Takeshi; Hamada, Mayuko; Hisata, Kanako; Tanaka, Makiko; Fujie, Manabu; Fujiwara, Mayuki; Koyanagi, Ryo; Ikuta, Tetsuro; Fujiyama, Asao; Miller, David J.; Satoh, Nori.

In: Nature, Vol. 476, No. 7360, 18.08.2011, p. 320-323.

Research output: Contribution to journalArticle

Shinzato, C, Shoguchi, E, Kawashima, T, Hamada, M, Hisata, K, Tanaka, M, Fujie, M, Fujiwara, M, Koyanagi, R, Ikuta, T, Fujiyama, A, Miller, DJ & Satoh, N 2011, 'Using the Acropora digitifera genome to understand coral responses to environmental change', Nature, vol. 476, no. 7360, pp. 320-323. https://doi.org/10.1038/nature10249
Shinzato C, Shoguchi E, Kawashima T, Hamada M, Hisata K, Tanaka M et al. Using the Acropora digitifera genome to understand coral responses to environmental change. Nature. 2011 Aug 18;476(7360):320-323. https://doi.org/10.1038/nature10249
Shinzato, Chuya ; Shoguchi, Eiichi ; Kawashima, Takeshi ; Hamada, Mayuko ; Hisata, Kanako ; Tanaka, Makiko ; Fujie, Manabu ; Fujiwara, Mayuki ; Koyanagi, Ryo ; Ikuta, Tetsuro ; Fujiyama, Asao ; Miller, David J. ; Satoh, Nori. / Using the Acropora digitifera genome to understand coral responses to environmental change. In: Nature. 2011 ; Vol. 476, No. 7360. pp. 320-323.
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