Usefulness of massive oral nicorandil in a patient with variant angina refractory to conventional treatment

Satoshi Kurisu, Ichiro Inoue, Takuji Kawagoe, Masaharu Ishihara, Yuji Shimatani, Kenji Nishioka, Shuji Nakamura, Takashi Umemura, Masashi Yoshida

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

A 67-year-old man, who was previously diagnosed with vasospastic angina and treated with standard therapy, was admitted to our hospital because of recurrent chest pain refractory to sublingual nitroglycerin. Admission electrocardiography revealed ST segment elevation in II, III and aVF, and his symptoms were relieved by intravenous bolus administration of nicorandil. He was diagnosed to have active variant angina, and remained symptomatic even after treatment with calcium antagonists and nitrates at optimal doses. Intravenous bolus administration of nicorandil was consistently effective to relieve his symptoms. Anginal attack was finally prevented by massive oral nicorandil in addition to conventional treatment.

Original languageEnglish
Pages (from-to)163-167
Number of pages5
JournalInternal Medicine
Volume42
Issue number2
DOIs
Publication statusPublished - Feb 1 2003
Externally publishedYes

Keywords

  • Chest pain
  • Coronary spasm
  • Electrocardiography
  • ST segment

ASJC Scopus subject areas

  • Internal Medicine

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    Kurisu, S., Inoue, I., Kawagoe, T., Ishihara, M., Shimatani, Y., Nishioka, K., Nakamura, S., Umemura, T., & Yoshida, M. (2003). Usefulness of massive oral nicorandil in a patient with variant angina refractory to conventional treatment. Internal Medicine, 42(2), 163-167. https://doi.org/10.2169/internalmedicine.42.163