Use of plasma B-type natriuretic peptide level to identify asymptomatic hypertensive patients with abnormal diurnal blood pressure variation profiles

Nondippers, extreme dippers, and risers

Takaaki Nakatsu, Ryouko Shinohata, Keiichi Mashima, Yoko Yuki, Aya Nishitani, Shinji Toyonaga, Hiroko Ogawa, Satoshi Hirohata, Shinichi Usui, Shozo Kusachi

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

We examined the relationship between plasma B-type natriuretic peptide (BNP) level and diurnal variability pattern of blood pressure (BP). Twenty-four-hour ambulatory BP monitoring was performed in 98 patients with asymptomatic essential hypertension, and the patients were classified into four groups according to their circadian BP variation profiles: dippers (n=29), nondippers (n=36), extreme dippers (n=19), and risers (n=14). Plasma BNP was measured by enzyme immunoassay. Based on the distribution pattern of BNP values, the values were analyzed after logarithmic transformation. Significant differences in plasma BNP levels among the types of circadian BP variations were demonstrated by analysis of variance (p

Original languageEnglish
Pages (from-to)651-658
Number of pages8
JournalHypertension Research
Volume30
Issue number7
DOIs
Publication statusPublished - Jul 2007

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Brain Natriuretic Peptide
Blood Pressure
Ambulatory Blood Pressure Monitoring
Immunoenzyme Techniques
Analysis of Variance

Keywords

  • Ambulatory blood pressure monitoring
  • Clinical study
  • Essential hypertension
  • Immunoassay
  • Peptide

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Use of plasma B-type natriuretic peptide level to identify asymptomatic hypertensive patients with abnormal diurnal blood pressure variation profiles : Nondippers, extreme dippers, and risers. / Nakatsu, Takaaki; Shinohata, Ryouko; Mashima, Keiichi; Yuki, Yoko; Nishitani, Aya; Toyonaga, Shinji; Ogawa, Hiroko; Hirohata, Satoshi; Usui, Shinichi; Kusachi, Shozo.

In: Hypertension Research, Vol. 30, No. 7, 07.2007, p. 651-658.

Research output: Contribution to journalArticle

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