TY - JOUR
T1 - Use of peptide aptamers, cationic peptides and artificial zinc finger proteins to generate resistance to plant viruses
AU - Sera, Takashi
N1 - Publisher Copyright:
© 2017 Elsevier B.V.
PY - 2017/10
Y1 - 2017/10
N2 - Various RNA/DNA viruses have caused severe infectious diseases in plants as well as animals, including humans, and been a threat to the production of agricultural crops. Therefore, prevention of plant virus infections is a major objective in crop protection. One attractive approach is to inhibit functions of viral proteins responsible for virus infections. In this review, I describe the status using such approaches to confer virus resistance to plants by three types of peptides/proteins: peptide aptamers, artificial zinc finger proteins and acidic peptides. These approaches vary in their specificity, broadness to other viruses, extent of protection and mechanisms of action. Additional ways to improve these approaches are also discussed.
AB - Various RNA/DNA viruses have caused severe infectious diseases in plants as well as animals, including humans, and been a threat to the production of agricultural crops. Therefore, prevention of plant virus infections is a major objective in crop protection. One attractive approach is to inhibit functions of viral proteins responsible for virus infections. In this review, I describe the status using such approaches to confer virus resistance to plants by three types of peptides/proteins: peptide aptamers, artificial zinc finger proteins and acidic peptides. These approaches vary in their specificity, broadness to other viruses, extent of protection and mechanisms of action. Additional ways to improve these approaches are also discussed.
UR - http://www.scopus.com/inward/record.url?scp=85028033204&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85028033204&partnerID=8YFLogxK
U2 - 10.1016/j.coviro.2017.07.023
DO - 10.1016/j.coviro.2017.07.023
M3 - Review article
C2 - 28806695
AN - SCOPUS:85028033204
VL - 26
SP - 120
EP - 124
JO - Current Opinion in Virology
JF - Current Opinion in Virology
SN - 1879-6257
ER -