Urinary uric acid excretion in term and premature infants

Hirokazu Tsukahara, M. Hiraoka, C. Hori, S. Tsuchida, H. Uchida, K. Fujisawa, Y. Konishi, M. Sudo

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Objective: To clarify postnatal changes in urinary uric acid (UA) excretion in normal term infants and to examine the effects of prematurity or illness on the UA excretion. Methodology: Measurements of urinary UA were performed in term and premature infants at the ages of 1 and 7 days and at 1 and 4 months, as well as at 7 months in term infants. Results: Urinary UA levels were lowest on day 7 in term infants. The levels were highest on day 1 in premature infants and remained significantly higher compared to term babies during the first month of life. Respiratory failure requiring ventilation and oxygen supply resulted in further significant elevation of urinary UA in premature infants. Conclusions: With the reference values obtained in the study reported here, urinary UA can now be used for the diagnosis and monitoring of inherited disorders of purine metabolism and for the assessment of oxygen radical insult to sick infants.

Original languageEnglish
Pages (from-to)330-332
Number of pages3
JournalJournal of Paediatrics and Child Health
Volume32
Issue number4
Publication statusPublished - 1996
Externally publishedYes

Fingerprint

Uric Acid
Premature Infants
Respiratory Insufficiency
Ventilation
Reactive Oxygen Species
Reference Values
Oxygen

Keywords

  • Infants
  • Oxygen radical
  • Prematurity
  • Purine metabolism
  • Uric acid

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Tsukahara, H., Hiraoka, M., Hori, C., Tsuchida, S., Uchida, H., Fujisawa, K., ... Sudo, M. (1996). Urinary uric acid excretion in term and premature infants. Journal of Paediatrics and Child Health, 32(4), 330-332.

Urinary uric acid excretion in term and premature infants. / Tsukahara, Hirokazu; Hiraoka, M.; Hori, C.; Tsuchida, S.; Uchida, H.; Fujisawa, K.; Konishi, Y.; Sudo, M.

In: Journal of Paediatrics and Child Health, Vol. 32, No. 4, 1996, p. 330-332.

Research output: Contribution to journalArticle

Tsukahara, H, Hiraoka, M, Hori, C, Tsuchida, S, Uchida, H, Fujisawa, K, Konishi, Y & Sudo, M 1996, 'Urinary uric acid excretion in term and premature infants', Journal of Paediatrics and Child Health, vol. 32, no. 4, pp. 330-332.
Tsukahara H, Hiraoka M, Hori C, Tsuchida S, Uchida H, Fujisawa K et al. Urinary uric acid excretion in term and premature infants. Journal of Paediatrics and Child Health. 1996;32(4):330-332.
Tsukahara, Hirokazu ; Hiraoka, M. ; Hori, C. ; Tsuchida, S. ; Uchida, H. ; Fujisawa, K. ; Konishi, Y. ; Sudo, M. / Urinary uric acid excretion in term and premature infants. In: Journal of Paediatrics and Child Health. 1996 ; Vol. 32, No. 4. pp. 330-332.
@article{f03766af5a054d31b3b82589d13818e7,
title = "Urinary uric acid excretion in term and premature infants",
abstract = "Objective: To clarify postnatal changes in urinary uric acid (UA) excretion in normal term infants and to examine the effects of prematurity or illness on the UA excretion. Methodology: Measurements of urinary UA were performed in term and premature infants at the ages of 1 and 7 days and at 1 and 4 months, as well as at 7 months in term infants. Results: Urinary UA levels were lowest on day 7 in term infants. The levels were highest on day 1 in premature infants and remained significantly higher compared to term babies during the first month of life. Respiratory failure requiring ventilation and oxygen supply resulted in further significant elevation of urinary UA in premature infants. Conclusions: With the reference values obtained in the study reported here, urinary UA can now be used for the diagnosis and monitoring of inherited disorders of purine metabolism and for the assessment of oxygen radical insult to sick infants.",
keywords = "Infants, Oxygen radical, Prematurity, Purine metabolism, Uric acid",
author = "Hirokazu Tsukahara and M. Hiraoka and C. Hori and S. Tsuchida and H. Uchida and K. Fujisawa and Y. Konishi and M. Sudo",
year = "1996",
language = "English",
volume = "32",
pages = "330--332",
journal = "Journal of Paediatrics and Child Health",
issn = "1034-4810",
publisher = "Wiley-Blackwell",
number = "4",

}

TY - JOUR

T1 - Urinary uric acid excretion in term and premature infants

AU - Tsukahara, Hirokazu

AU - Hiraoka, M.

AU - Hori, C.

AU - Tsuchida, S.

AU - Uchida, H.

AU - Fujisawa, K.

AU - Konishi, Y.

AU - Sudo, M.

PY - 1996

Y1 - 1996

N2 - Objective: To clarify postnatal changes in urinary uric acid (UA) excretion in normal term infants and to examine the effects of prematurity or illness on the UA excretion. Methodology: Measurements of urinary UA were performed in term and premature infants at the ages of 1 and 7 days and at 1 and 4 months, as well as at 7 months in term infants. Results: Urinary UA levels were lowest on day 7 in term infants. The levels were highest on day 1 in premature infants and remained significantly higher compared to term babies during the first month of life. Respiratory failure requiring ventilation and oxygen supply resulted in further significant elevation of urinary UA in premature infants. Conclusions: With the reference values obtained in the study reported here, urinary UA can now be used for the diagnosis and monitoring of inherited disorders of purine metabolism and for the assessment of oxygen radical insult to sick infants.

AB - Objective: To clarify postnatal changes in urinary uric acid (UA) excretion in normal term infants and to examine the effects of prematurity or illness on the UA excretion. Methodology: Measurements of urinary UA were performed in term and premature infants at the ages of 1 and 7 days and at 1 and 4 months, as well as at 7 months in term infants. Results: Urinary UA levels were lowest on day 7 in term infants. The levels were highest on day 1 in premature infants and remained significantly higher compared to term babies during the first month of life. Respiratory failure requiring ventilation and oxygen supply resulted in further significant elevation of urinary UA in premature infants. Conclusions: With the reference values obtained in the study reported here, urinary UA can now be used for the diagnosis and monitoring of inherited disorders of purine metabolism and for the assessment of oxygen radical insult to sick infants.

KW - Infants

KW - Oxygen radical

KW - Prematurity

KW - Purine metabolism

KW - Uric acid

UR - http://www.scopus.com/inward/record.url?scp=0030209240&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030209240&partnerID=8YFLogxK

M3 - Article

C2 - 8844540

AN - SCOPUS:0030209240

VL - 32

SP - 330

EP - 332

JO - Journal of Paediatrics and Child Health

JF - Journal of Paediatrics and Child Health

SN - 1034-4810

IS - 4

ER -