TY - JOUR
T1 - Urinary nitrite/nitrate excretion in infancy
T2 - Comparison between term and preterm infants
AU - Tsukahara, Hirokazu
AU - Hiraoka, Masahiro
AU - Hori, Chikahide
AU - Tsuchida, Shinya
AU - Hata, Ikeue
AU - Nishida, Kouichi
AU - Kikuchi, Kiyoshi
AU - Sudo, Masakatsu
PY - 1997
Y1 - 1997
N2 - We measured urinary nitrite/nitrate (NOx-) excretion, an index of endogenous nitric oxide formation, in term and preterm infants aged 1 week and 1, 4, 7 months, In normal term infants, urinary NOx- excretion increased from 1 week to 1 month and then decreased until 4 months where it stabilized thereafter. Urinary NOx- excretion in preterm infants was significantly higher compared with term infants at 1 week of age. This finding suggests that the nitric oxide pathway in preterm infants may be activated compared with term infants in early life. With the reference values obtained in this study, this urinary marker can now be used for identifying infants with abnormal nitric oxide production.
AB - We measured urinary nitrite/nitrate (NOx-) excretion, an index of endogenous nitric oxide formation, in term and preterm infants aged 1 week and 1, 4, 7 months, In normal term infants, urinary NOx- excretion increased from 1 week to 1 month and then decreased until 4 months where it stabilized thereafter. Urinary NOx- excretion in preterm infants was significantly higher compared with term infants at 1 week of age. This finding suggests that the nitric oxide pathway in preterm infants may be activated compared with term infants in early life. With the reference values obtained in this study, this urinary marker can now be used for identifying infants with abnormal nitric oxide production.
KW - Infant
KW - NO and NO
KW - Nitric oxide
KW - Urine
UR - http://www.scopus.com/inward/record.url?scp=0031019736&partnerID=8YFLogxK
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U2 - 10.1016/S0378-3782(96)01768-9
DO - 10.1016/S0378-3782(96)01768-9
M3 - Article
C2 - 9118828
AN - SCOPUS:0031019736
VL - 47
SP - 51
EP - 56
JO - Screening
JF - Screening
SN - 0378-3782
IS - 1
ER -