Urinary N-acetyl-beta-D-glucosaminidase excretion in term and preterm neonates

Hirokazu Tsukahara, C. Hori, S. Tsuchida, M. Hiraoka, M. Sudo, S. Haruki, F. Suehiro

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Urinary N-acetyl-beta-D-glucosaminidase (NAG) excretion was measured in term and preterm neonates on days 1, 4,7,14 and 28 of life. Urinary NAG showed a peak level on day 4 or 7 in these infants. In addition, it tended to be higher with the degree of prematurity. In sick preterms who were depressed at birth and had respiratory faliure, the NAG activity was further elevated during the first 2 weeks, suggesting the presence of renal tubular injury in this period. These observations thus suggest that urinary NAG may be a sensitive measure of renal maturation or damage in neonates.

Original languageEnglish
Pages (from-to)536-538
Number of pages3
JournalJournal of Paediatrics and Child Health
Issue number6
Publication statusPublished - 1994
Externally publishedYes



  • N-acetyl-beta-D-glucosaminidase
  • Neonates
  • Prematurity
  • Renal tubular damage

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Tsukahara, H., Hori, C., Tsuchida, S., Hiraoka, M., Sudo, M., Haruki, S., & Suehiro, F. (1994). Urinary N-acetyl-beta-D-glucosaminidase excretion in term and preterm neonates. Journal of Paediatrics and Child Health, 30(6), 536-538.