Urinary excretion of aquaporin-2 in term and preterm infants

Hirokazu Tsukahara, Ikue Hata, Kyoichi Sekine, Masakazu Miura, Keishi Hata, Yasushi Fujii, Mitsufumi Mayumi

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Aquaporin-2 (AQP-2) is a vasopressin-regulated water channel of the renal collecting duct and is excreted in human urine. We measured the urinary excretion of AQP-2 by radioimmunoassay in 14 term and 12 preterm infants aged 1 month. Excretion of AQP-2 was low compared with adults, and correlated significantly with urine osmolality in preterm infants. Our results demonstrate that AQP-2 water channels are expressed in the renal collecting duct of both term and preterm infants.

Original languageEnglish
Pages (from-to)31-37
Number of pages7
JournalEarly Human Development
Volume51
Issue number1
DOIs
Publication statusPublished - Apr 17 1998
Externally publishedYes

Fingerprint

Aquaporin 2
Premature Infants
Urine
Kidney
Aquaporins
Vasopressins
Osmolar Concentration
Radioimmunoassay

Keywords

  • Aquaporin-2
  • Infants
  • Urine
  • Vasopressin
  • Water balance

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Tsukahara, H., Hata, I., Sekine, K., Miura, M., Hata, K., Fujii, Y., & Mayumi, M. (1998). Urinary excretion of aquaporin-2 in term and preterm infants. Early Human Development, 51(1), 31-37. https://doi.org/10.1016/S0378-3782(97)00072-8

Urinary excretion of aquaporin-2 in term and preterm infants. / Tsukahara, Hirokazu; Hata, Ikue; Sekine, Kyoichi; Miura, Masakazu; Hata, Keishi; Fujii, Yasushi; Mayumi, Mitsufumi.

In: Early Human Development, Vol. 51, No. 1, 17.04.1998, p. 31-37.

Research output: Contribution to journalArticle

Tsukahara, H, Hata, I, Sekine, K, Miura, M, Hata, K, Fujii, Y & Mayumi, M 1998, 'Urinary excretion of aquaporin-2 in term and preterm infants', Early Human Development, vol. 51, no. 1, pp. 31-37. https://doi.org/10.1016/S0378-3782(97)00072-8
Tsukahara, Hirokazu ; Hata, Ikue ; Sekine, Kyoichi ; Miura, Masakazu ; Hata, Keishi ; Fujii, Yasushi ; Mayumi, Mitsufumi. / Urinary excretion of aquaporin-2 in term and preterm infants. In: Early Human Development. 1998 ; Vol. 51, No. 1. pp. 31-37.
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