Urea sensor based on an ammonium-ion-sensitive field-effect transistor

Yuji Miyahara, Keiji Tsukada, Hiroyuki Miyagi, Wilhelm Simon

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

A urea sensor based on an ammonium-ion-sensitive field-effect transistor has been realized in combination with an immobilized urease membrane. The effect of buffer concentrations on the response characteristics of the sensor is investigated. The lower detection limit, as given by the calibration curve, is strongly affected by the concentrations of potassium and sodium ions, while its slope in the appropriate buffer solution is independent of the buffer concentration in a limited urea concentration range. Although the slope in physiological saline solution is only 18 mV/dec, the dynamic range of the sensor covers the physiological range of urea in blood. The small slope and the narrow dynamic range are found to be due to poor selectivity of the ammonium-ion-selective membrane over sodium and potassium ions. It is, therefore, possible to improve the sensor response characteristics by improving the selectivity of the ammonium-ion-selective membrane.

Original languageEnglish
Pages (from-to)287-293
Number of pages7
JournalSensors and Actuators, B: Chemical
Volume3
Issue number4
DOIs
Publication statusPublished - 1991
Externally publishedYes

Fingerprint

Ion sensitive field effect transistors
ureas
Ammonium Compounds
Urea
field effect transistors
Ion selective membranes
Buffers
sensors
Sensors
buffers
Potassium
slopes
ions
membranes
Sodium
dynamic range
Ions
potassium
selectivity
sodium

ASJC Scopus subject areas

  • Analytical Chemistry
  • Electrochemistry
  • Electrical and Electronic Engineering

Cite this

Urea sensor based on an ammonium-ion-sensitive field-effect transistor. / Miyahara, Yuji; Tsukada, Keiji; Miyagi, Hiroyuki; Simon, Wilhelm.

In: Sensors and Actuators, B: Chemical, Vol. 3, No. 4, 1991, p. 287-293.

Research output: Contribution to journalArticle

Miyahara, Yuji ; Tsukada, Keiji ; Miyagi, Hiroyuki ; Simon, Wilhelm. / Urea sensor based on an ammonium-ion-sensitive field-effect transistor. In: Sensors and Actuators, B: Chemical. 1991 ; Vol. 3, No. 4. pp. 287-293.
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