Uptakes of trace elements in Zn-deficient mice

T. Ohyama, M. Yanaga, T. Yoshida, H. Maetsu, M. Noguchi, H. Suganuma, T. Omori, R. Hirunuma, S. Enomoto

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A multitracer technique was used to obtain uptake rates of essential trace elements in various organs and tissues in Zn-deficient mice. A multitracer solution, containing more than 20 radioisotopes, was injected intraperitoneally into Zn-deficient state mice and control ones. Uptake rates of the radioisotopes were compared with concentrations of trace elements determined by instrumental neutron activation analysis (INAA) in order to study a specific metabolism of Zn and other essential trace elements, such as Mn, Co, Se, Rb, and Sr. The result suggests that Zn is supplied from bone to other organs and tissues and an increase in Co concentration in all organs and tissues depends on its chemical form, under the Z-deficient state.

Original languageEnglish
Pages (from-to)393-398
Number of pages6
JournalJournal of Radioanalytical and Nuclear Chemistry
Issue number3
Publication statusPublished - Apr 11 2002

ASJC Scopus subject areas

  • Analytical Chemistry
  • Nuclear Energy and Engineering
  • Radiology Nuclear Medicine and imaging
  • Pollution
  • Spectroscopy
  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis

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  • Cite this

    Ohyama, T., Yanaga, M., Yoshida, T., Maetsu, H., Noguchi, M., Suganuma, H., Omori, T., Hirunuma, R., & Enomoto, S. (2002). Uptakes of trace elements in Zn-deficient mice. Journal of Radioanalytical and Nuclear Chemistry, 251(3), 393-398. https://doi.org/10.1023/A:1014869822530