TY - JOUR
T1 - Uptakes of trace elements in Zn-deficient mice
AU - Ohyama, T.
AU - Yanaga, M.
AU - Yoshida, T.
AU - Maetsu, H.
AU - Noguchi, M.
AU - Suganuma, H.
AU - Omori, T.
AU - Hirunuma, R.
AU - Enomoto, S.
N1 - Funding Information:
We are grateful to RIKEN multitracer group for separation of multitracer solution from Ag target. We wish to thank Mr. M. IWAMA for his cooperation in this experiment. This work was supported in part by Grant-in-Aid for Scientific Research (c) (No.11640561) from Japan Society for the Promotion of Science to T. O. and M. Y.
PY - 2002
Y1 - 2002
N2 - A multitracer technique was used to obtain uptake rates of essential trace elements in various organs and tissues in Zn-deficient mice. A multitracer solution, containing more than 20 radioisotopes, was injected intraperitoneally into Zn-deficient state mice and control ones. Uptake rates of the radioisotopes were compared with concentrations of trace elements determined by instrumental neutron activation analysis (INAA) in order to study a specific metabolism of Zn and other essential trace elements, such as Mn, Co, Se, Rb, and Sr. The result suggests that Zn is supplied from bone to other organs and tissues and an increase in Co concentration in all organs and tissues depends on its chemical form, under the Z-deficient state.
AB - A multitracer technique was used to obtain uptake rates of essential trace elements in various organs and tissues in Zn-deficient mice. A multitracer solution, containing more than 20 radioisotopes, was injected intraperitoneally into Zn-deficient state mice and control ones. Uptake rates of the radioisotopes were compared with concentrations of trace elements determined by instrumental neutron activation analysis (INAA) in order to study a specific metabolism of Zn and other essential trace elements, such as Mn, Co, Se, Rb, and Sr. The result suggests that Zn is supplied from bone to other organs and tissues and an increase in Co concentration in all organs and tissues depends on its chemical form, under the Z-deficient state.
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U2 - 10.1023/A:1014869822530
DO - 10.1023/A:1014869822530
M3 - Article
AN - SCOPUS:0036193745
VL - 251
SP - 393
EP - 398
JO - Journal of Radioanalytical Chemistry
JF - Journal of Radioanalytical Chemistry
SN - 0022-4081
IS - 3
ER -
