Unique behavior of rubidium in mice under low oxygen atmosphere simultaneous tracing of Sc, Mn, Fe, Co, Zn, Se, Rb, Y, and Zr using the radioactive multitracer technique

Relative tissue distributions of Sc, Mn, Fe, Co, Zn, Se, Rb, Y, and Zr tracers were studied in young mice housed under four different O₂ atmospheres (10 percent, 20 percent, 80 percent, and 100 percent O₂) using the radioactive multitracer technique developed at The Institute of Physical and Chemical Research (RIKEN). At 48 hr after injection of the multitracer, the tissue uptake rates were examined for 10 tissues (brain, cardiac muscle, lung, liver, spleen, pancreas, kidneys, skeletal muscle, bone, and blood) and expressed as the radioactivity percentage of the injected dose per gram of wet tissue (percent dose/g). Rubidium uptake rates for all soft tissues of mice housed under a 10 percent O₂ atmosphere were found to be higher than those of the tissues of mice housed under the other three O₂ atmospheres (20 percent, 80 percent, and 100 percent), but no difference was observed for the other elements (Sc, Mn, Fe, Co, Se, etc.) under any of the O₂ atmospheres.