TY - JOUR
T1 - Unique antimicrobial spectrum of ophiobolin K produced by Aspergillus ustus
AU - Sohsomboon, Natthapat
AU - Kanzaki, Hiroshi
AU - Nitoda, Teruhiko
N1 - Publisher Copyright:
© 2018 Japan society for Bioscience, Biotechnology, and agrochemistry.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2018
Y1 - 2018
N2 - A co-cultivation study of two fungal strains showed that Aspergillus ustus could inhibit Aspergillus repens growth. The bioactive compound responsible for the observed activity was purified and identified as a sesterterpene, ophiobolin K. Ophiobolin K exhibited marked inhibition against both fungi and bacteria, especially A. repens, A. glaucus and gram-positive bacteria including Bacillus subtilis, Staphylococcus aureus, and Micrococcus luteus.
AB - A co-cultivation study of two fungal strains showed that Aspergillus ustus could inhibit Aspergillus repens growth. The bioactive compound responsible for the observed activity was purified and identified as a sesterterpene, ophiobolin K. Ophiobolin K exhibited marked inhibition against both fungi and bacteria, especially A. repens, A. glaucus and gram-positive bacteria including Bacillus subtilis, Staphylococcus aureus, and Micrococcus luteus.
KW - Antifungal activity
KW - Co-cultivation
KW - Sesterterpene
UR - http://www.scopus.com/inward/record.url?scp=85044223482&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85044223482&partnerID=8YFLogxK
U2 - 10.1080/09168451.2018.1429890
DO - 10.1080/09168451.2018.1429890
M3 - Article
C2 - 29375031
AN - SCOPUS:85044223482
VL - 82
SP - 422
EP - 424
JO - Bioscience, Biotechnology and Biochemistry
JF - Bioscience, Biotechnology and Biochemistry
SN - 0916-8451
IS - 3
ER -