Unique antimicrobial spectrum of ophiobolin K produced by Aspergillus ustus

Natthapat Sohsomboon, Hiroshi Kanzaki, Teruhiko Nitoda

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


A co-cultivation study of two fungal strains showed that Aspergillus ustus could inhibit Aspergillus repens growth. The bioactive compound responsible for the observed activity was purified and identified as a sesterterpene, ophiobolin K. Ophiobolin K exhibited marked inhibition against both fungi and bacteria, especially A. repens, A. glaucus and gram-positive bacteria including Bacillus subtilis, Staphylococcus aureus, and Micrococcus luteus.

Original languageEnglish
Pages (from-to)422-424
Number of pages3
JournalBioscience, Biotechnology and Biochemistry
Issue number3
Publication statusPublished - 2018


  • Antifungal activity
  • Co-cultivation
  • Sesterterpene

ASJC Scopus subject areas

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry


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