Unique antimicrobial spectrum of ophiobolin K produced by Aspergillus ustus

Natthapat Sohsomboon, Hiroshi Kanzaki, Teruhiko Nitoda

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

A co-cultivation study of two fungal strains showed that Aspergillus ustus could inhibit Aspergillus repens growth. The bioactive compound responsible for the observed activity was purified and identified as a sesterterpene, ophiobolin K. Ophiobolin K exhibited marked inhibition against both fungi and bacteria, especially A. repens, A. glaucus and gram-positive bacteria including Bacillus subtilis, Staphylococcus aureus, and Micrococcus luteus.

Original languageEnglish
Pages (from-to)422-424
Number of pages3
JournalBioscience, Biotechnology and Biochemistry
Volume82
Issue number3
DOIs
Publication statusPublished - Jan 1 2018

Fingerprint

Aspergillus
Sesterterpenes
Bacteria
Micrococcus luteus
Gram-Positive Bacteria
Bacilli
Bacillus subtilis
Fungi
Staphylococcus aureus
Growth
ophiobolins

Keywords

  • Antifungal activity
  • Co-cultivation
  • Sesterterpene

ASJC Scopus subject areas

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

Cite this

Unique antimicrobial spectrum of ophiobolin K produced by Aspergillus ustus. / Sohsomboon, Natthapat; Kanzaki, Hiroshi; Nitoda, Teruhiko.

In: Bioscience, Biotechnology and Biochemistry, Vol. 82, No. 3, 01.01.2018, p. 422-424.

Research output: Contribution to journalArticle

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