Uncariagambiriines B and C, alkaloid-catechin hybrids from Uncaria gambir leaves

Mutsumi Oshima, Hiroe Aoyama, Yuuki Shimozu, Shoko Taniguchi, Takanori Miura, Tsutomu Hatano

Research output: Contribution to journalArticle

Abstract

– Gambiers, aqueous extracts from the leaves and twigs of Uncaria gambir, are used medicinally in Asian countries. Previously, we reported the isolation of uncariagambiriine (1) from U. gambir leaves, and its unique structure regarded as a catechin-alkaloid hybrid. Our continuing studies led to the isolation of two previously undescribed compounds named uncariagambiriines B (2) and C (3), in addition to the flavonoid glycosides, hyperoside and isoquercitrin. The structures of 2 and 3, isomeric to 1, were elucidated based on their spectral data.

Original languageEnglish
Pages (from-to)804-812
Number of pages9
JournalHeterocycles
Volume98
Issue number6
DOIs
Publication statusPublished - Jan 1 2019

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ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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