Ultrastructure of Warthin-Starry Stain-Positive Bacteria in Abscess-Forming Reticular Lymphadenitis

Y. Ohtani, T. Yoshirio, T. Akagi

Research output: Contribution to journalArticlepeer-review

Abstract

This study describes the ultrastructure of Warthin-Starry (WS) stain-positive bacteria in abscess-forming reticular lymphadenitis (ARL) compatible with cat scratch disease (CSD). Sections containing WS-positive bacteria were re-embedded in Epon, andsemithin sections were examined by electron microscopy. Silver particles were aggregated on the outer surfaces of the bacteria. Stereoscopic observations clearly showed that the bacteria were pleomorphic, rod-shaped, arranged in a row or at an angle, and frequently showed septal formation. Electron microscopy of ultrathin sections revealed that the cell wall possessed an outer membrane characteristic of gram-negative bacteria. The results indicate that rod-shaped bacteria with the WS-positive, gram-negative staining cause ARL histopathologically consistent with CSD.

Original languageEnglish
Pages (from-to)314-317
Number of pages4
JournalPathology Research and Practice
Volume188
Issue number3
DOIs
Publication statusPublished - 1992

Keywords

  • Cat scratch disease bacteria
  • Lymphadenitis
  • Stereoscopic electron microscopy
  • Warthin-Starry stain

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Cell Biology

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