Tyrokeradines C-F, new bromotyrosine alkaloids from the Verongid sponges

Takaaki Kubota, Shinya Watase, Hiroya Mukai, Jane Fromont, Jun'ichi Kobayashi

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

Four new bromotyrosine alkaloids, tyrokeradines C-F (1-4), have been isolated from Okinawan marine sponges of the order Verongidae. The structures of 1-4 were elucidated on the basis of spectroscopic data. Tyrokeradines C (1) and D (2) are new bromotyrosine alkaloids possesing an imidazole ring, while tyrokeradines E (3) and F (4) are new bromotyrosine alkaloids possesing a cyano group.

Original languageEnglish
Pages (from-to)1599-1601
Number of pages3
JournalChemical and Pharmaceutical Bulletin
Volume60
Issue number12
DOIs
Publication statusPublished - 2012
Externally publishedYes

Keywords

  • Bromotyrosine alkaloid
  • Marine sponge
  • Order Verongida
  • Tyrokeradine

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

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