Tyrokeradines C-F, new bromotyrosine alkaloids from the Verongid sponges

Takaaki Kubota; Shinya Watase; Hiroya Mukai; Jane Fromont; Jun'ichi Kobayashi

doi:10.1248/cpb.c12-00785

Tyrokeradines C-F, new bromotyrosine alkaloids from the Verongid sponges

Takaaki Kubota, Shinya Watase, Hiroya Mukai, Jane Fromont, Jun'ichi Kobayashi

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

Four new bromotyrosine alkaloids, tyrokeradines C-F (1-4), have been isolated from Okinawan marine sponges of the order Verongidae. The structures of 1-4 were elucidated on the basis of spectroscopic data. Tyrokeradines C (1) and D (2) are new bromotyrosine alkaloids possesing an imidazole ring, while tyrokeradines E (3) and F (4) are new bromotyrosine alkaloids possesing a cyano group.

Original language	English
Pages (from-to)	1599-1601
Number of pages	3
Journal	Chemical and Pharmaceutical Bulletin
Volume	60
Issue number	12
DOIs	https://doi.org/10.1248/cpb.c12-00785
Publication status	Published - 2012
Externally published	Yes

Keywords

Bromotyrosine alkaloid
Marine sponge
Order Verongida
Tyrokeradine

ASJC Scopus subject areas

Chemistry(all)
Drug Discovery

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1248/cpb.c12-00785

Cite this

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abstract = "Four new bromotyrosine alkaloids, tyrokeradines C-F (1-4), have been isolated from Okinawan marine sponges of the order Verongidae. The structures of 1-4 were elucidated on the basis of spectroscopic data. Tyrokeradines C (1) and D (2) are new bromotyrosine alkaloids possesing an imidazole ring, while tyrokeradines E (3) and F (4) are new bromotyrosine alkaloids possesing a cyano group.",

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author = "Takaaki Kubota and Shinya Watase and Hiroya Mukai and Jane Fromont and Jun'ichi Kobayashi",

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doi = "10.1248/cpb.c12-00785",

language = "English",

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pages = "1599--1601",

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T1 - Tyrokeradines C-F, new bromotyrosine alkaloids from the Verongid sponges

AU - Kubota, Takaaki

AU - Watase, Shinya

AU - Mukai, Hiroya

AU - Fromont, Jane

AU - Kobayashi, Jun'ichi

PY - 2012

Y1 - 2012

N2 - Four new bromotyrosine alkaloids, tyrokeradines C-F (1-4), have been isolated from Okinawan marine sponges of the order Verongidae. The structures of 1-4 were elucidated on the basis of spectroscopic data. Tyrokeradines C (1) and D (2) are new bromotyrosine alkaloids possesing an imidazole ring, while tyrokeradines E (3) and F (4) are new bromotyrosine alkaloids possesing a cyano group.

AB - Four new bromotyrosine alkaloids, tyrokeradines C-F (1-4), have been isolated from Okinawan marine sponges of the order Verongidae. The structures of 1-4 were elucidated on the basis of spectroscopic data. Tyrokeradines C (1) and D (2) are new bromotyrosine alkaloids possesing an imidazole ring, while tyrokeradines E (3) and F (4) are new bromotyrosine alkaloids possesing a cyano group.

KW - Bromotyrosine alkaloid

KW - Marine sponge

KW - Order Verongida

KW - Tyrokeradine

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JO - Chemical and Pharmaceutical Bulletin

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ER -

Tyrokeradines C-F, new bromotyrosine alkaloids from the Verongid sponges

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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