Tyrokeradines A and B, new bromotyrosine alkaloids with an imidazolyl-quinolinone moiety from a Verongid sponge

Hiroya Mukai, Takaaki Kubota, Kazuki Aoyama, Yuzuru Mikami, Jane Fromont, Jun'ichi Kobayashi

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)

Abstract

Two new bromotyrosine alkaloids, tyrokeradines A (1) and B (2), with an imidazolyl-quinolinone moiety have been isolated from an Okinawan marine sponge of the order Verongida. The structures of 1 and 2 were elucidated on the basis of spectroscopic data.

Original languageEnglish
Pages (from-to)1337-1339
Number of pages3
JournalBioorganic and Medicinal Chemistry Letters
Volume19
Issue number5
DOIs
Publication statusPublished - Mar 1 2009
Externally publishedYes

Keywords

  • Bromotyrosine alkaloids
  • Tyrokeradines A and B
  • Verongid sponge

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

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