Two-year results of reduced-fluence photodynamic therapy for polypoidal choroidal vasculopathy

Ayana Yamashita, Fumio Shiraga, Chieko Shiragami, Yukari Shirakata, Atsushi Fujiwara

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Purpose: To report the results of a 2-year follow-up study of Japanese polypoidal choroidal vasculopathy (PCV) patients treated with reduced-fluence photodynamic therapy (PDT) monotherapy. Design: Prospective interventional case series. Methods: In the present study, 38 eyes of 38 consecutive patients underwent PDT with a reduced laser fluence of 25 J/cm2. During the 2-year follow-up, visual acuity (VA) and optical coherence tomography measurements were performed every 3 months after the PDT procedure and then compared with baseline values. PCV vascular lesions were evaluated by indocyanine green and fluorescein angiography. Results: At baseline, the mean logarithm of the minimal angle of resolution (logMAR) best-corrected VA (BCVA) was 0.43. There was a significant improvement of the mean logMAR BCVA to 0.28 and 0.29 at 12 and 24 months, respectively (P

Original languageEnglish
Pages (from-to)96-102
Number of pages7
JournalAmerican Journal of Ophthalmology
Volume155
Issue number1
DOIs
Publication statusPublished - Jan 2013
Externally publishedYes

Fingerprint

Photochemotherapy
Visual Acuity
Indocyanine Green
Fluorescein Angiography
Optical Coherence Tomography
Blood Vessels
Lasers

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Two-year results of reduced-fluence photodynamic therapy for polypoidal choroidal vasculopathy. / Yamashita, Ayana; Shiraga, Fumio; Shiragami, Chieko; Shirakata, Yukari; Fujiwara, Atsushi.

In: American Journal of Ophthalmology, Vol. 155, No. 1, 01.2013, p. 96-102.

Research output: Contribution to journalArticle

Yamashita, Ayana ; Shiraga, Fumio ; Shiragami, Chieko ; Shirakata, Yukari ; Fujiwara, Atsushi. / Two-year results of reduced-fluence photodynamic therapy for polypoidal choroidal vasculopathy. In: American Journal of Ophthalmology. 2013 ; Vol. 155, No. 1. pp. 96-102.
@article{5b9e89de31f04728bc0b8fd653d91584,
title = "Two-year results of reduced-fluence photodynamic therapy for polypoidal choroidal vasculopathy",
abstract = "Purpose: To report the results of a 2-year follow-up study of Japanese polypoidal choroidal vasculopathy (PCV) patients treated with reduced-fluence photodynamic therapy (PDT) monotherapy. Design: Prospective interventional case series. Methods: In the present study, 38 eyes of 38 consecutive patients underwent PDT with a reduced laser fluence of 25 J/cm2. During the 2-year follow-up, visual acuity (VA) and optical coherence tomography measurements were performed every 3 months after the PDT procedure and then compared with baseline values. PCV vascular lesions were evaluated by indocyanine green and fluorescein angiography. Results: At baseline, the mean logarithm of the minimal angle of resolution (logMAR) best-corrected VA (BCVA) was 0.43. There was a significant improvement of the mean logMAR BCVA to 0.28 and 0.29 at 12 and 24 months, respectively (P",
author = "Ayana Yamashita and Fumio Shiraga and Chieko Shiragami and Yukari Shirakata and Atsushi Fujiwara",
year = "2013",
month = "1",
doi = "10.1016/j.ajo.2012.06.027",
language = "English",
volume = "155",
pages = "96--102",
journal = "American Journal of Ophthalmology",
issn = "0002-9394",
publisher = "Elsevier USA",
number = "1",

}

TY - JOUR

T1 - Two-year results of reduced-fluence photodynamic therapy for polypoidal choroidal vasculopathy

AU - Yamashita, Ayana

AU - Shiraga, Fumio

AU - Shiragami, Chieko

AU - Shirakata, Yukari

AU - Fujiwara, Atsushi

PY - 2013/1

Y1 - 2013/1

N2 - Purpose: To report the results of a 2-year follow-up study of Japanese polypoidal choroidal vasculopathy (PCV) patients treated with reduced-fluence photodynamic therapy (PDT) monotherapy. Design: Prospective interventional case series. Methods: In the present study, 38 eyes of 38 consecutive patients underwent PDT with a reduced laser fluence of 25 J/cm2. During the 2-year follow-up, visual acuity (VA) and optical coherence tomography measurements were performed every 3 months after the PDT procedure and then compared with baseline values. PCV vascular lesions were evaluated by indocyanine green and fluorescein angiography. Results: At baseline, the mean logarithm of the minimal angle of resolution (logMAR) best-corrected VA (BCVA) was 0.43. There was a significant improvement of the mean logMAR BCVA to 0.28 and 0.29 at 12 and 24 months, respectively (P

AB - Purpose: To report the results of a 2-year follow-up study of Japanese polypoidal choroidal vasculopathy (PCV) patients treated with reduced-fluence photodynamic therapy (PDT) monotherapy. Design: Prospective interventional case series. Methods: In the present study, 38 eyes of 38 consecutive patients underwent PDT with a reduced laser fluence of 25 J/cm2. During the 2-year follow-up, visual acuity (VA) and optical coherence tomography measurements were performed every 3 months after the PDT procedure and then compared with baseline values. PCV vascular lesions were evaluated by indocyanine green and fluorescein angiography. Results: At baseline, the mean logarithm of the minimal angle of resolution (logMAR) best-corrected VA (BCVA) was 0.43. There was a significant improvement of the mean logMAR BCVA to 0.28 and 0.29 at 12 and 24 months, respectively (P

UR - http://www.scopus.com/inward/record.url?scp=84871216204&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84871216204&partnerID=8YFLogxK

U2 - 10.1016/j.ajo.2012.06.027

DO - 10.1016/j.ajo.2012.06.027

M3 - Article

VL - 155

SP - 96

EP - 102

JO - American Journal of Ophthalmology

JF - American Journal of Ophthalmology

SN - 0002-9394

IS - 1

ER -