Two-year results of reduced-fluence photodynamic therapy for polypoidal choroidal vasculopathy

Ayana Yamashita, Fumio Shiraga, Chieko Shiragami, Yukari Shirakata, Atsushi Fujiwara

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Purpose: To report the results of a 2-year follow-up study of Japanese polypoidal choroidal vasculopathy (PCV) patients treated with reduced-fluence photodynamic therapy (PDT) monotherapy. Design: Prospective interventional case series. Methods: In the present study, 38 eyes of 38 consecutive patients underwent PDT with a reduced laser fluence of 25 J/cm2. During the 2-year follow-up, visual acuity (VA) and optical coherence tomography measurements were performed every 3 months after the PDT procedure and then compared with baseline values. PCV vascular lesions were evaluated by indocyanine green and fluorescein angiography. Results: At baseline, the mean logarithm of the minimal angle of resolution (logMAR) best-corrected VA (BCVA) was 0.43. There was a significant improvement of the mean logMAR BCVA to 0.28 and 0.29 at 12 and 24 months, respectively (P

Original languageEnglish
Pages (from-to)96-102
Number of pages7
JournalAmerican Journal of Ophthalmology
Issue number1
Publication statusPublished - Jan 2013
Externally publishedYes


ASJC Scopus subject areas

  • Ophthalmology

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