Abstract
We report two cases of anti-glutamic acid receptor (anti-GluR) antibody-positive encephalitis in males with symptoms such as Parkinsonism, urinary retention, and paralytic ileus. Although non-herpetic encephalitis typically shows magnetic resonance imaging (MRI) lesions in the limbic system during early stages, the present cases showed MRI lesions during later stages in the bilateral claustrum and pons. In both cases, anti-GluRε2 and δ2 antibodies were later shown to be positive in the cerebrospinal fuid but negative in the serum. Although early detection of anti-GluR antibodies is essential, early treatment may be signifcantly more important.
| Original language | English |
|---|---|
| Pages (from-to) | 113-117 |
| Number of pages | 5 |
| Journal | Clinical Medicine Insights: Case Reports |
| Volume | 6 |
| DOIs | |
| Publication status | Published - 2013 |
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Keywords
- Anti-GluR antibody-positive encephalitis
- Autonomic failure
- MRI
- Parkinsonism
ASJC Scopus subject areas
- Medicine(all)
Cite this
Two unique cases with anti-GluR antibody-positive encephalitis. / Matsuzono, Kosuke; Kurata, Tomoko; Deguchi, Shoko; Yamashita, Toru; Deguchi, Kentaro; Ikeda, Yoshio; Abe, Koji.
In: Clinical Medicine Insights: Case Reports, Vol. 6, 2013, p. 113-117.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Two unique cases with anti-GluR antibody-positive encephalitis
AU - Matsuzono, Kosuke
AU - Kurata, Tomoko
AU - Deguchi, Shoko
AU - Yamashita, Toru
AU - Deguchi, Kentaro
AU - Ikeda, Yoshio
AU - Abe, Koji
PY - 2013
Y1 - 2013
N2 - We report two cases of anti-glutamic acid receptor (anti-GluR) antibody-positive encephalitis in males with symptoms such as Parkinsonism, urinary retention, and paralytic ileus. Although non-herpetic encephalitis typically shows magnetic resonance imaging (MRI) lesions in the limbic system during early stages, the present cases showed MRI lesions during later stages in the bilateral claustrum and pons. In both cases, anti-GluRε2 and δ2 antibodies were later shown to be positive in the cerebrospinal fuid but negative in the serum. Although early detection of anti-GluR antibodies is essential, early treatment may be signifcantly more important.
AB - We report two cases of anti-glutamic acid receptor (anti-GluR) antibody-positive encephalitis in males with symptoms such as Parkinsonism, urinary retention, and paralytic ileus. Although non-herpetic encephalitis typically shows magnetic resonance imaging (MRI) lesions in the limbic system during early stages, the present cases showed MRI lesions during later stages in the bilateral claustrum and pons. In both cases, anti-GluRε2 and δ2 antibodies were later shown to be positive in the cerebrospinal fuid but negative in the serum. Although early detection of anti-GluR antibodies is essential, early treatment may be signifcantly more important.
KW - Anti-GluR antibody-positive encephalitis
KW - Autonomic failure
KW - MRI
KW - Parkinsonism
UR - http://www.scopus.com/inward/record.url?scp=84879473813&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84879473813&partnerID=8YFLogxK
U2 - 10.4137/CCRep.S11890
DO - 10.4137/CCRep.S11890
M3 - Article
VL - 6
SP - 113
EP - 117
JO - Clinical Medicine Insights: Case Reports
JF - Clinical Medicine Insights: Case Reports
SN - 1179-5476
ER -