Two unique cases with anti-GluR antibody-positive encephalitis

Kosuke Matsuzono, Tomoko Kurata, Shoko Deguchi, Toru Yamashita, Kentaro Deguchi, Yoshio Ikeda, Koji Abe

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We report two cases of anti-glutamic acid receptor (anti-GluR) antibody-positive encephalitis in males with symptoms such as Parkinsonism, urinary retention, and paralytic ileus. Although non-herpetic encephalitis typically shows magnetic resonance imaging (MRI) lesions in the limbic system during early stages, the present cases showed MRI lesions during later stages in the bilateral claustrum and pons. In both cases, anti-GluRε2 and δ2 antibodies were later shown to be positive in the cerebrospinal fuid but negative in the serum. Although early detection of anti-GluR antibodies is essential, early treatment may be signifcantly more important.

Original languageEnglish
Pages (from-to)113-117
Number of pages5
JournalClinical Medicine Insights: Case Reports
Volume6
DOIs
Publication statusPublished - 2013

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Keywords

  • Anti-GluR antibody-positive encephalitis
  • Autonomic failure
  • MRI
  • Parkinsonism

ASJC Scopus subject areas

  • Medicine(all)

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