Abstract
Two new taxanes were isolated from the MeOH extract of the needles and branches bark of the Japanese yew, Taxus cuspidata. The structures were established as (2α,5α,7β,9α,10β,13α)- 5,10,13,20-tetraacetoxytax-11-ene-2,7,9-triol (1) and (2α,5α,9α,10β)-2,9, 10-triacetoxy-5-[(β-D-glucopyranosyl)oxy] -3,11-cyclotax-11-en-13-one (2) on the basis of in-depth 1D- and 2D-NMR analyses (Tables 1-3, Fig. 1). Compound 2 is the first example of a transannular taxane glycoside isolated from a natural source.
Original language | English |
---|---|
Pages (from-to) | 1153-1161 |
Number of pages | 9 |
Journal | Chemistry and Biodiversity |
Volume | 3 |
Issue number | 10 |
DOIs | |
Publication status | Published - Nov 10 2006 |
Externally published | Yes |
ASJC Scopus subject areas
- Bioengineering
- Biochemistry
- Chemistry(all)
- Molecular Medicine
- Molecular Biology