Two new taxanes from the needles and branches bark of Taxus cuspidata

Cong Mei Cao; Man Li Zhang; Yu Fang Wang; Qing Wen Shi; Teiko Yamada; Hiromasa Kiyota

doi:10.1002/cbdv.200690117

Two new taxanes from the needles and branches bark of Taxus cuspidata

Cong Mei Cao, Man Li Zhang, Yu Fang Wang, Qing Wen Shi, Teiko Yamada, Hiromasa Kiyota

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

Two new taxanes were isolated from the MeOH extract of the needles and branches bark of the Japanese yew, Taxus cuspidata. The structures were established as (2α,5α,7β,9α,10β,13α)- 5,10,13,20-tetraacetoxytax-11-ene-2,7,9-triol (1) and (2α,5α,9α,10β)-2,9, 10-triacetoxy-5-[(β-D-glucopyranosyl)oxy] -3,11-cyclotax-11-en-13-one (2) on the basis of in-depth 1D- and 2D-NMR analyses (Tables 1-3, Fig. 1). Compound 2 is the first example of a transannular taxane glycoside isolated from a natural source.

Original language	English
Pages (from-to)	1153-1161
Number of pages	9
Journal	Chemistry and Biodiversity
Volume	3
Issue number	10
DOIs	https://doi.org/10.1002/cbdv.200690117
Publication status	Published - Nov 10 2006
Externally published	Yes

ASJC Scopus subject areas

Bioengineering
Biochemistry
Chemistry(all)
Molecular Medicine
Molecular Biology

Access to Document

10.1002/cbdv.200690117

Fingerprint Dive into the research topics of 'Two new taxanes from the needles and branches bark of Taxus cuspidata'. Together they form a unique fingerprint.

Cite this

@article{29ef1a03b2184d00ba55e90850517d7e,

title = "Two new taxanes from the needles and branches bark of Taxus cuspidata",

abstract = "Two new taxanes were isolated from the MeOH extract of the needles and branches bark of the Japanese yew, Taxus cuspidata. The structures were established as (2α,5α,7β,9α,10β,13α)- 5,10,13,20-tetraacetoxytax-11-ene-2,7,9-triol (1) and (2α,5α,9α,10β)-2,9, 10-triacetoxy-5-[(β-D-glucopyranosyl)oxy] -3,11-cyclotax-11-en-13-one (2) on the basis of in-depth 1D- and 2D-NMR analyses (Tables 1-3, Fig. 1). Compound 2 is the first example of a transannular taxane glycoside isolated from a natural source.",

author = "Cao, {Cong Mei} and Zhang, {Man Li} and Wang, {Yu Fang} and Shi, {Qing Wen} and Teiko Yamada and Hiromasa Kiyota",

year = "2006",

month = nov,

day = "10",

doi = "10.1002/cbdv.200690117",

language = "English",

volume = "3",

pages = "1153--1161",

journal = "Chemistry and Biodiversity",

issn = "1612-1872",

publisher = "Wiley-VCH Verlag",

number = "10",

}

TY - JOUR

T1 - Two new taxanes from the needles and branches bark of Taxus cuspidata

AU - Cao, Cong Mei

AU - Zhang, Man Li

AU - Wang, Yu Fang

AU - Shi, Qing Wen

AU - Yamada, Teiko

AU - Kiyota, Hiromasa

PY - 2006/11/10

Y1 - 2006/11/10

N2 - Two new taxanes were isolated from the MeOH extract of the needles and branches bark of the Japanese yew, Taxus cuspidata. The structures were established as (2α,5α,7β,9α,10β,13α)- 5,10,13,20-tetraacetoxytax-11-ene-2,7,9-triol (1) and (2α,5α,9α,10β)-2,9, 10-triacetoxy-5-[(β-D-glucopyranosyl)oxy] -3,11-cyclotax-11-en-13-one (2) on the basis of in-depth 1D- and 2D-NMR analyses (Tables 1-3, Fig. 1). Compound 2 is the first example of a transannular taxane glycoside isolated from a natural source.

AB - Two new taxanes were isolated from the MeOH extract of the needles and branches bark of the Japanese yew, Taxus cuspidata. The structures were established as (2α,5α,7β,9α,10β,13α)- 5,10,13,20-tetraacetoxytax-11-ene-2,7,9-triol (1) and (2α,5α,9α,10β)-2,9, 10-triacetoxy-5-[(β-D-glucopyranosyl)oxy] -3,11-cyclotax-11-en-13-one (2) on the basis of in-depth 1D- and 2D-NMR analyses (Tables 1-3, Fig. 1). Compound 2 is the first example of a transannular taxane glycoside isolated from a natural source.

UR - http://www.scopus.com/inward/record.url?scp=33750610988&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33750610988&partnerID=8YFLogxK

U2 - 10.1002/cbdv.200690117

DO - 10.1002/cbdv.200690117

M3 - Article

C2 - 17193230

AN - SCOPUS:33750610988

VL - 3

SP - 1153

EP - 1161

JO - Chemistry and Biodiversity

JF - Chemistry and Biodiversity

SN - 1612-1872

IS - 10

ER -

Two new taxanes from the needles and branches bark of Taxus cuspidata

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Cite this