Two new taxanes from the needles and branches bark of Taxus cuspidata

Cong Mei Cao, Man Li Zhang, Yu Fang Wang, Qing Wen Shi, Teiko Yamada, Hiromasa Kiyota

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Two new taxanes were isolated from the MeOH extract of the needles and branches bark of the Japanese yew, Taxus cuspidata. The structures were established as (2α,5α,7β,9α,10β,13α)- 5,10,13,20-tetraacetoxytax-11-ene-2,7,9-triol (1) and (2α,5α,9α,10β)-2,9, 10-triacetoxy-5-[(β-D-glucopyranosyl)oxy] -3,11-cyclotax-11-en-13-one (2) on the basis of in-depth 1D- and 2D-NMR analyses (Tables 1-3, Fig. 1). Compound 2 is the first example of a transannular taxane glycoside isolated from a natural source.

Original languageEnglish
Pages (from-to)1153-1161
Number of pages9
JournalChemistry and Biodiversity
Volume3
Issue number10
DOIs
Publication statusPublished - 2006
Externally publishedYes

Fingerprint

Taxus
Glycosides
Taxoids
Needles
Nuclear magnetic resonance
taxane

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Molecular Medicine

Cite this

Two new taxanes from the needles and branches bark of Taxus cuspidata. / Cao, Cong Mei; Zhang, Man Li; Wang, Yu Fang; Shi, Qing Wen; Yamada, Teiko; Kiyota, Hiromasa.

In: Chemistry and Biodiversity, Vol. 3, No. 10, 2006, p. 1153-1161.

Research output: Contribution to journalArticle

Cao, Cong Mei ; Zhang, Man Li ; Wang, Yu Fang ; Shi, Qing Wen ; Yamada, Teiko ; Kiyota, Hiromasa. / Two new taxanes from the needles and branches bark of Taxus cuspidata. In: Chemistry and Biodiversity. 2006 ; Vol. 3, No. 10. pp. 1153-1161.
@article{29ef1a03b2184d00ba55e90850517d7e,
title = "Two new taxanes from the needles and branches bark of Taxus cuspidata",
abstract = "Two new taxanes were isolated from the MeOH extract of the needles and branches bark of the Japanese yew, Taxus cuspidata. The structures were established as (2α,5α,7β,9α,10β,13α)- 5,10,13,20-tetraacetoxytax-11-ene-2,7,9-triol (1) and (2α,5α,9α,10β)-2,9, 10-triacetoxy-5-[(β-D-glucopyranosyl)oxy] -3,11-cyclotax-11-en-13-one (2) on the basis of in-depth 1D- and 2D-NMR analyses (Tables 1-3, Fig. 1). Compound 2 is the first example of a transannular taxane glycoside isolated from a natural source.",
author = "Cao, {Cong Mei} and Zhang, {Man Li} and Wang, {Yu Fang} and Shi, {Qing Wen} and Teiko Yamada and Hiromasa Kiyota",
year = "2006",
doi = "10.1002/cbdv.200690117",
language = "English",
volume = "3",
pages = "1153--1161",
journal = "Chemistry and Biodiversity",
issn = "1612-1872",
publisher = "Wiley-VCH Verlag",
number = "10",

}

TY - JOUR

T1 - Two new taxanes from the needles and branches bark of Taxus cuspidata

AU - Cao, Cong Mei

AU - Zhang, Man Li

AU - Wang, Yu Fang

AU - Shi, Qing Wen

AU - Yamada, Teiko

AU - Kiyota, Hiromasa

PY - 2006

Y1 - 2006

N2 - Two new taxanes were isolated from the MeOH extract of the needles and branches bark of the Japanese yew, Taxus cuspidata. The structures were established as (2α,5α,7β,9α,10β,13α)- 5,10,13,20-tetraacetoxytax-11-ene-2,7,9-triol (1) and (2α,5α,9α,10β)-2,9, 10-triacetoxy-5-[(β-D-glucopyranosyl)oxy] -3,11-cyclotax-11-en-13-one (2) on the basis of in-depth 1D- and 2D-NMR analyses (Tables 1-3, Fig. 1). Compound 2 is the first example of a transannular taxane glycoside isolated from a natural source.

AB - Two new taxanes were isolated from the MeOH extract of the needles and branches bark of the Japanese yew, Taxus cuspidata. The structures were established as (2α,5α,7β,9α,10β,13α)- 5,10,13,20-tetraacetoxytax-11-ene-2,7,9-triol (1) and (2α,5α,9α,10β)-2,9, 10-triacetoxy-5-[(β-D-glucopyranosyl)oxy] -3,11-cyclotax-11-en-13-one (2) on the basis of in-depth 1D- and 2D-NMR analyses (Tables 1-3, Fig. 1). Compound 2 is the first example of a transannular taxane glycoside isolated from a natural source.

UR - http://www.scopus.com/inward/record.url?scp=33750610988&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33750610988&partnerID=8YFLogxK

U2 - 10.1002/cbdv.200690117

DO - 10.1002/cbdv.200690117

M3 - Article

VL - 3

SP - 1153

EP - 1161

JO - Chemistry and Biodiversity

JF - Chemistry and Biodiversity

SN - 1612-1872

IS - 10

ER -