Two new taxanes from the needles and branches bark of Taxus cuspidata

Cong Mei Cao; Man Li Zhang; Yu Fang Wang; Qing Wen Shi; Teiko Yamada; Hiromasa Kiyota

doi:10.1002/cbdv.200690117

Two new taxanes from the needles and branches bark of Taxus cuspidata

Cong Mei Cao, Man Li Zhang, Yu Fang Wang, Qing Wen Shi, Teiko Yamada, Hiromasa Kiyota

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

Two new taxanes were isolated from the MeOH extract of the needles and branches bark of the Japanese yew, Taxus cuspidata. The structures were established as (2α,5α,7β,9α,10β,13α)- 5,10,13,20-tetraacetoxytax-11-ene-2,7,9-triol (1) and (2α,5α,9α,10β)-2,9, 10-triacetoxy-5-[(β-D-glucopyranosyl)oxy] -3,11-cyclotax-11-en-13-one (2) on the basis of in-depth 1D- and 2D-NMR analyses (Tables 1-3, Fig. 1). Compound 2 is the first example of a transannular taxane glycoside isolated from a natural source.

Original language	English
Pages (from-to)	1153-1161
Number of pages	9
Journal	Chemistry and Biodiversity
Volume	3
Issue number	10
DOIs	https://doi.org/10.1002/cbdv.200690117
Publication status	Published - Nov 10 2006
Externally published	Yes

ASJC Scopus subject areas

Bioengineering
Biochemistry
Chemistry(all)
Molecular Medicine
Molecular Biology

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Cite this

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abstract = "Two new taxanes were isolated from the MeOH extract of the needles and branches bark of the Japanese yew, Taxus cuspidata. The structures were established as (2α,5α,7β,9α,10β,13α)- 5,10,13,20-tetraacetoxytax-11-ene-2,7,9-triol (1) and (2α,5α,9α,10β)-2,9, 10-triacetoxy-5-[(β-D-glucopyranosyl)oxy] -3,11-cyclotax-11-en-13-one (2) on the basis of in-depth 1D- and 2D-NMR analyses (Tables 1-3, Fig. 1). Compound 2 is the first example of a transannular taxane glycoside isolated from a natural source.",

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AU - Cao, Cong Mei

AU - Zhang, Man Li

AU - Wang, Yu Fang

AU - Shi, Qing Wen

AU - Yamada, Teiko

AU - Kiyota, Hiromasa

PY - 2006/11/10

Y1 - 2006/11/10

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Two new taxanes from the needles and branches bark of Taxus cuspidata

Abstract

ASJC Scopus subject areas

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