Two new taxane-glycosides from the needles of Taxus canadensis

Nan Li, Jin Wang, Hui Min Yan, Man Li Zhang, Qing Wen Shi, Francoise Sauriol, Hiromasa Kiyota, Mei Dong

Research output: Contribution to journalArticle

Abstract

Two minor taxane glycosides were isolated for the first time from the needles of Taxus canadensis. Their structures were characterized as 2α,5α-diacetoxy- 10β-(6'-O-acetyl-β-d-glucopyranosyl) oxy-14β-[(2'R,3'S)- 3'-hydroxy-2'-methylbutanoyl]oxytaxa-4(20),11-diene (1) and 2α, 14β-diacetoxy-10β-(β-d-glucopyranosyl) oxytaxa- 4(20),11-dien-5β-ol (2) on the basis of 1D and 2D NMR data analysis and confirmed by high-resolution fast atom bombardment mass spectrometry.

Original languageEnglish
Pages (from-to)829-835
Number of pages7
JournalZeitschrift fur Naturforschung - Section B Journal of Chemical Sciences
Volume70
Issue number11
DOIs
Publication statusPublished - Nov 1 2015

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Keywords

  • Glucosides
  • Structure determination
  • Taxanes
  • Taxus canadensis
  • Yew

ASJC Scopus subject areas

  • Chemistry(all)

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