Two new alkaloidal taxoids from the needles of Taxus canadensis

Qing Wen Shi, Xiao Tang Si, Yong Ming Zhao, Xiao Hui Su, Xing Li, Lolita O. Zamir, Teiko Yamada, Hiromasa Kiyota

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Two new taxanes with a dimethylamino group on the C-5 side chain were identified for the first time in the needles of the Canadian yew, Taxus canadensis. Their structures were characterized as 7β,10β,13α- triacetoxy-5α-(3′-dimethylaimno-3′-phenylpropanoyl) -oxy-2α-hydroxy-2(3→20)abeotaxa-4(20),11-dien-9-one (1) and 2α,10β-diacetoxy-9α-hydroxy-5α-(3′-dimethylamino- 3′-phenylpropanoyl)oxy-3,11-cyclotax-4(20)-en-13-one (2).

Original languageEnglish
Pages (from-to)732-736
Number of pages5
JournalBioscience, Biotechnology and Biochemistry
Volume70
Issue number3
DOIs
Publication statusPublished - Mar 31 2006
Externally publishedYes

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Keywords

  • 2(3→20)abeotaxane
  • 3,11-cyclotaxane
  • Taxanes
  • Taxus canadensis Marsh

ASJC Scopus subject areas

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

Cite this

Shi, Q. W., Si, X. T., Zhao, Y. M., Su, X. H., Li, X., Zamir, L. O., Yamada, T., & Kiyota, H. (2006). Two new alkaloidal taxoids from the needles of Taxus canadensis. Bioscience, Biotechnology and Biochemistry, 70(3), 732-736. https://doi.org/10.1271/bbb.70.732