Two new alkaloidal taxoids from the needles of Taxus canadensis

Qing Wen Shi, Xiao Tang Si, Yong Ming Zhao, Xiao Hui Su, Xing Li, Lolita O. Zamir, Teiko Yamada, Hiromasa Kiyota

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Two new taxanes with a dimethylamino group on the C-5 side chain were identified for the first time in the needles of the Canadian yew, Taxus canadensis. Their structures were characterized as 7β,10β,13α- triacetoxy-5α-(3′-dimethylaimno-3′-phenylpropanoyl) -oxy-2α-hydroxy-2(3→20)abeotaxa-4(20),11-dien-9-one (1) and 2α,10β-diacetoxy-9α-hydroxy-5α-(3′-dimethylamino- 3′-phenylpropanoyl)oxy-3,11-cyclotax-4(20)-en-13-one (2).

Original languageEnglish
Pages (from-to)732-736
Number of pages5
JournalBioscience, Biotechnology and Biochemistry
Volume70
Issue number3
DOIs
Publication statusPublished - 2006
Externally publishedYes

Fingerprint

Taxus canadensis
Taxus
taxanes
Taxoids
Needles

Keywords

  • 2(3→20)abeotaxane
  • 3,11-cyclotaxane
  • Taxanes
  • Taxus canadensis Marsh

ASJC Scopus subject areas

  • Bioengineering
  • Biotechnology
  • Biochemistry
  • Biochemistry, Genetics and Molecular Biology(all)
  • Chemistry (miscellaneous)
  • Applied Microbiology and Biotechnology
  • Food Science

Cite this

Two new alkaloidal taxoids from the needles of Taxus canadensis. / Shi, Qing Wen; Si, Xiao Tang; Zhao, Yong Ming; Su, Xiao Hui; Li, Xing; Zamir, Lolita O.; Yamada, Teiko; Kiyota, Hiromasa.

In: Bioscience, Biotechnology and Biochemistry, Vol. 70, No. 3, 2006, p. 732-736.

Research output: Contribution to journalArticle

Shi, QW, Si, XT, Zhao, YM, Su, XH, Li, X, Zamir, LO, Yamada, T & Kiyota, H 2006, 'Two new alkaloidal taxoids from the needles of Taxus canadensis', Bioscience, Biotechnology and Biochemistry, vol. 70, no. 3, pp. 732-736. https://doi.org/10.1271/bbb.70.732
Shi, Qing Wen ; Si, Xiao Tang ; Zhao, Yong Ming ; Su, Xiao Hui ; Li, Xing ; Zamir, Lolita O. ; Yamada, Teiko ; Kiyota, Hiromasa. / Two new alkaloidal taxoids from the needles of Taxus canadensis. In: Bioscience, Biotechnology and Biochemistry. 2006 ; Vol. 70, No. 3. pp. 732-736.
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AU - Yamada, Teiko

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