TY - CHAP
T1 - Two-Component Signaling in the Virulence of Staphylococcus aureus
T2 - A Silkworm Larvae-Pathogenic Agent Infection Model of Virulence
AU - Kurokawa, Kenji
AU - Kaito, Chikara
AU - Sekimizu, Kazuhisa
PY - 2007/1/1
Y1 - 2007/1/1
N2 - Staphylococcus aureus is a pathogenic bacterium that causes abscesses, pneumonia, endocarditis, and food poisoning. S. aureus is also one of the resident flora of the endotherm and colonizes the host by skillfully evading its defense mechanism. Identification of attenuated mutants of S. aureus in an animal infection model is useful for investigating its adaptability and pathogenesis. This chapter describes a staphylococcal two-component SA0614-SA0615 system, which was identified using a silkworm larvae infection model.
AB - Staphylococcus aureus is a pathogenic bacterium that causes abscesses, pneumonia, endocarditis, and food poisoning. S. aureus is also one of the resident flora of the endotherm and colonizes the host by skillfully evading its defense mechanism. Identification of attenuated mutants of S. aureus in an animal infection model is useful for investigating its adaptability and pathogenesis. This chapter describes a staphylococcal two-component SA0614-SA0615 system, which was identified using a silkworm larvae infection model.
UR - http://www.scopus.com/inward/record.url?scp=34447106508&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34447106508&partnerID=8YFLogxK
U2 - 10.1016/S0076-6879(06)22011-1
DO - 10.1016/S0076-6879(06)22011-1
M3 - Chapter
C2 - 17628142
AN - SCOPUS:34447106508
T3 - Methods in Enzymology
SP - 233
EP - 244
BT - Two Component Signaling Systems, Part A
PB - Academic Press Inc.
ER -